CAR-T Operations Technician at Legend Biotech

Ghent, Flanders, Belgium

Legend Biotech Logo
Not SpecifiedCompensation
Junior (1 to 2 years)Experience Level
Full TimeJob Type
UnknownVisa
BiotechnologyIndustries

Requirements

  • Bachelor's or Master's degree in sciences, (bio)engineering, biotechnology, pharmacy, or a related field, or equivalent through experience
  • Practical experience within a cGMP or ATMP environment and with aseptic techniques in clean rooms is an asset, but not mandatory (training will be provided)
  • Fluent in Dutch or English, with strong oral and written communication skills
  • Knowledge of cGMP regulations and clean room activities

Responsibilities

  • Accurately perform steps in the CAR-T manufacturing process, including cell culture, purification, aseptic processing, and cryopreservation
  • Follow Standard Operating Procedures (SOPs) and batch records to ensure the quality and safety of cellular therapies
  • Work closely with various teams and departments to complete production tasks according to a shift schedule
  • Contribute to process optimizations and efficiency improvements
  • Maintain GMP production areas, focusing on equipment cleanliness and environmental monitoring
  • Complete all necessary GMP documents to ensure compliance and traceability

Skills

Key technologies and capabilities for this role

cGMPaseptic processingcell culturepurificationcryopreservationclean room operationsGMP documentationSOPsbatch recordsenvironmental monitoring

Questions & Answers

Common questions about this position

What is the salary for the CAR-T Operations Technician position?

This information is not specified in the job description.

Is this role remote or onsite, and where is it located?

The position is onsite in Ghent.

What education and experience are required for this role?

A Bachelor's or Master's degree in sciences, (bio)engineering, biotechnology, pharmacy, or related field is required, or equivalent experience. Practical experience in cGMP or ATMP environments and aseptic techniques is an asset but not mandatory, with training provided.

What is the work schedule and company culture like?

The role follows a 4 days on, 4 days off schedule for work-life balance in a supportive, innovative environment that values learning, personal development, and working with an international team.

What benefits are offered with this position?

It includes an open-ended contract with an attractive salary package, additional statutory vacations, meal vouchers, group and hospitalization insurance, double vacation pay, end-of-year bonus, and performance bonus.

Legend Biotech

Develops and commercializes cell therapies

About Legend Biotech

Legend Biotech develops and commercializes cell therapies aimed at treating serious diseases, particularly cancers like hematological malignancies and solid tumors. Their approach is technology agnostic, allowing them to explore various methods to find effective treatments. The company operates in the personalized medicine sector, focusing on discovering, developing, and bringing new therapies to market. They generate revenue through licensing and selling their therapies, including CAR-T therapies, which involve modifying a patient's cells to combat cancer. Legend Biotech emphasizes transparency with investors, regularly updating them on financial results and business developments.

Franklin Township, New JerseyHeadquarters
2014Year Founded
$146.4MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
1,001-5,000Employees

Benefits

Health Insurance
Dental Insurance
Vision Insurance
Life Insurance
Disability Insurance
Paid Sick Leave
Paid Holidays
Remote Work Options

Risks

Increased competition from Amgen's Imdelltra may impact CAR-T therapy focus.
Collaboration with Multiply Labs may face technological challenges, delaying production timelines.
Financial strain from new R&D facility could affect operational focus if advancements lag.

Differentiation

Legend Biotech focuses on novel cell therapies for oncology, including CAR-T and NK cells.
The company is technology agnostic, exploring multiple platforms for effective cancer treatments.
Legend Biotech's CARVYKTI® is the first BCMA-targeted CAR-T therapy approved for second-line use.

Upsides

Recent FDA and European approvals for CARVYKTI® expand its market reach in multiple myeloma.
New R&D facility in Philadelphia boosts innovation in next-generation cell therapies.
Alan Bash's appointment could accelerate CARVYKTI®'s growth and market penetration.

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