VP, Total Rewards, People Operations & Analytics at Dyno Therapeutics

Waltham, Massachusetts, United States

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Not SpecifiedCompensation

Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

BiotechnologyIndustries

Requirements

Based in Waltham, MA (no remote possibility)
Strategic and hands-on leadership experience in HR, particularly in total rewards, compensation, benefits, HR operations, HRIS, and people analytics
Expertise in global compensation philosophy, frameworks, planning, incentive design, equity strategy, and Board Compensation Committee interactions
Knowledge of competitive market intelligence, biotech equity practices, and pay-for-performance insights
Experience owning strategy and administration of health & welfare plans, retirement, time-off/leave programs, and wellbeing offerings
Proficiency in leading annual plan design/renewals, vendor management, fiduciary compliance, and benefits aligned to biotech standards
Deep experience with ADP Workforce Now (WFN) as core HRIS/payroll/benefits platform, including configuration, integrations, data integrity, and upgrades
Ability to manage employee lifecycle processes (hire-to-retire), onboarding/offboarding, compliance, multi-state/global payroll
Skills in vendor ecosystem management, SLAs, operational excellence, audit readiness, and regulatory compliance
Capability to drive HR systems innovation, automation, scalability, efficiency, and data accuracy

Responsibilities

Own Dyne’s global compensation philosophy and frameworks (market positioning, pay mix, salary structures, job architecture, geographic differentials)
Lead annual compensation planning (merit, promotions, adjustments), short- and long-term incentive design, sales/field comp as applicable, and equity strategy (grant guidelines, refresh cadence, burn rate/share pool stewardship)
Partner with the CHRO to prepare materials for and present to the Board Compensation Committee; provide external benchmarking, pay-for-performance insights, and risk/compliance guidance
Maintain competitive market intelligence (surveys, biotech equity practices), and advise on underwater equity, refresh approaches, and executive offers/retention mechanisms
Own strategy and administration of health & welfare plans, retirement, time-off/leave programs, and wellbeing offerings that reflect patient-centric culture and growth stage
Lead annual plan design/renewals, vendor management, fiduciary compliance, communications, and required testing/reporting
Ensure benefits and wellness programs align to biotech peer standards for attraction/retention
Lead People Operations function with focus on ADP Workforce Now (WFN): oversee system configuration, integrations, access control, data flows, maintenance, and upgrades
Ensure ADP WFN and integrated modules (HR, payroll, benefits, talent, time & attendance) support process scalability and data integrity
Stand up or refine processes across the employee lifecycle (hire-to-retire), including onboarding/offboarding, employee records, policy execution, compliance, and multi-state/global payroll in partnership with Legal/Finance
Own vendor ecosystem (benefits administration, brokers, payroll, HR tech); negotiate SLAs and performance
Deliver operational excellence that improves employee experience while ensuring accuracy, audit readiness, and regulatory compliance
Drive continuous innovation and intelligent automation across all HR systems and processes to enhance scalability, efficiency, and data accuracy as Dyne grows
Develop comprehensive total rewards and recognition programs, operations and analytics strategies aligned to Dyne’s people philosophy and culture
Build scalable programs and infrastructure; serve as key advisor to CHRO and Compensation Committee on competitive, equitable, compliant, insight-driven rewards and people systems

Skills

Key technologies and capabilities for this role

Compensation StrategyTotal RewardsHR OperationsPeople AnalyticsHRISExecutive CompensationIncentive DesignJob ArchitectureHR ComplianceBenefits AdministrationGlobal CompensationSalary Structures

Questions & Answers

Common questions about this position

Is this role remote or does it require being in the office?

This role is based in Waltham, MA without the possibility of being remote.

What is the salary or compensation for this position?

This information is not specified in the job description.

What key skills or experience are required for this VP role?

The role requires expertise in compensation philosophy and frameworks, benefits strategy and administration, people operations, HR compliance, HRIS, and people analytics, along with strategic leadership to align programs with company culture.

What is the company culture like at Dyne Therapeutics?

Dyne emphasizes a patient-centric culture, with total rewards and benefits programs designed to reflect this while aligning to the company's people philosophy, growth stage, and biotech peer standards.

What makes a strong candidate for this VP position?

A strong candidate will have hands-on leadership experience in building scalable compensation, benefits, HR operations, and analytics programs, with the ability to serve as a strategic advisor to the CHRO and Compensation Committee on competitive, equitable, and compliant systems.

Dyno Therapeutics

Develops AI-optimized gene therapy vectors

About Dyno Therapeutics

Dyno Therapeutics focuses on advancing gene therapy by utilizing Artificial Intelligence to create Adeno-associated virus (AAV) vectors. These vectors are essential tools for delivering genetic material into cells, which is crucial for effective gene therapy. The company's AI technology enables the design and optimization of these vectors, potentially enhancing the success of gene therapies. Dyno collaborates with major pharmaceutical and biotech companies, such as Astellas, Roche, Sarepta, and Novartis, to develop therapies for various diseases affecting the skeletal and cardiac muscles, central nervous system, liver, and eyes. Unlike many competitors, Dyno's unique approach leverages AI to improve the performance of AAV vectors, setting it apart in the biotech field. The company's goal is to improve gene therapy outcomes through its advanced vector technology, ultimately benefiting patients with serious health conditions.

Watertown, MassachusettsHeadquarters

2018Year Founded

$106MTotal Funding

SERIES_ACompany Stage

AI & Machine Learning, Biotechnology, HealthcareIndustries

51-200Employees

Benefits

Remote Work Options

Risks

Gene therapy investment slowdown may impact Dyno's growth and innovation.

Manufacturing bottlenecks could hinder scaling of Dyno's operations.

Increased competition from companies like Form Bio challenges Dyno's market position.

Differentiation

Dyno uses AI to design optimized AAV vectors for gene therapy.

Their AI-driven CapsidMap platform enhances AAV vector development for muscle gene therapies.

Partnerships with major pharma companies like Astellas and Roche boost Dyno's market presence.

Upsides

AI-driven capsid design improves delivery efficiency and reduces manufacturing costs.

Collaboration with NVIDIA enhances biological sequence design for gene therapies.

Generative AI increases efficiency of eye and brain-targeted capsid delivery significantly.

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