Sr Marketing Manager, Signatera GI Oncology

Position Summary

Natera is seeking a Senior Marketing Manager to lead marketing strategy and execution for Signatera, our personalized molecular residual disease (MRD) test, with a focus on gastrointestinal (GI) cancers. This role is critical in driving adoption and integration of Signatera into standard of care for GI oncology. The ideal candidate brings a passion for oncology innovation, deep marketing expertise, and the ability to communicate complex scientific value simply and effectively. This individual will report to the Associate Director Oncology Marketing, GI Cancers.

Travel: 30%

Primary Responsibilities

• Develop and execute strategic and tactical marketing plans to drive growth of Signatera in GI cancers and other solid tumors.
• Track and analyze product performance metrics to identify growth opportunities and close gaps to target.
• Lead the development of field and digital marketing collateral, ensuring alignment with current clinical data and strategic priorities.
• Ensure all GI-specific content on web and digital platforms reflects the latest scientific evidence and product messaging.
• Identify, engage, and manage partnerships with relevant third-party organizations offering educational or promotional opportunities.
• Collaborate cross-functionally with medical affairs, field sales, digital, regulatory, legal, and external vendors to execute on marketing initiatives.

Qualifications

• Bachelor’s degree in life sciences or related field required; advanced degree (MBA, PhD) preferred.
• 5–7 years of experience in product marketing, field sales, or market analytics within diagnostics, biotech, or pharmaceutical industries.
• Experience in oncology and/or genomics highly preferred.
• Familiarity with FDA-approved treatments and the clinical landscape in GI cancers is a strong plus.

Knowledge, Skills & Abilities

• Strategic thinker with strong business acumen and ability to operate with executive presence.
• Effective collaborator across internal teams and external stakeholders, including thought leaders.
• Strong customer orientation with an ability to distill complex scientific content into clear, value-driven messaging.
• Excellent written and verbal communication skills.
• Outstanding organizational and time management skills; ability to manage multiple projects simultaneously and deliver high-quality results.
• Demonstrated success in developing and managing key opinion leader relationships and external partnerships.
• Passion for improving patient care through innovative cancer diagnostics.

Compensation

San Carlos, CA: $150,000 - $190,000 USD Remote USA: $133,600 - $175,000 USD

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Our Opportunity

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that makes a difference.