Senior Scientist, Discovery Biology, Oncology Thematic Research Center at Bristol-Myers Squibb

Seattle, Washington, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Oncology, Biotechnology, PharmaceuticalsIndustries

Requirements

Bachelor’s Degree with 6+ years of relevant academic and/or industry experience, or Master’s Degree with 4+ years of relevant academic and/or industry experience, or Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience
Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience (preferred)
Knowledge of T cell biology and relevant in vitro assay systems; experience with transformed tumor cells (preferred)
Experience with technologies to engineer cell lines and assess immune cell function, including CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies (preferred)
Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation
Self-motivated and focused with project management-oriented thinking; able to work on multiple projects in a matrix environment
Ability to communicate well with peers, supervisors, and governance committees
Strong problem-solving skills and understanding of complex scientific principles
Strong organizational skills to ensure thorough and timely documentation of experiments and preparation of data

Responsibilities

Identify and validate novel targets for development of T cell engagers
Independently design, develop, and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers
Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles
Design and implement critical studies required to drive hypothesis-driven research
Collaborate across multiple projects/roles in a matrixed environment
Present complex concepts to a range of audiences including governance and full team project meetings
Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders

Skills

Key technologies and capabilities for this role

ImmunologyT Cell ImmunologyIn Vitro AssaysEx Vivo AssaysCell-Based AssaysTarget IdentificationTarget ValidationAssay DevelopmentOncology

Questions & Answers

Common questions about this position

What is the location for this Senior Scientist role?

The position is based in Seattle, WA, within the Oncology Thematic Research Center at Bristol Myers Squibb.

What are the basic qualifications for this position?

Basic qualifications include a Bachelor’s Degree with 6+ years of relevant experience, a Master’s Degree with 4+ years, or a Ph.D. in immunology, immuno-oncology, tumor immunology, or related field with 2+ years of experience.

What key responsibilities does this role involve?

The role involves identifying and validating novel targets for T cell engagers, designing and executing in vitro and ex vivo assays, applying T cell biology knowledge, and collaborating across matrixed teams.

What is the work environment like at Bristol Myers Squibb?

The environment is highly collaborative, dynamic, fast-paced, and matrixed, involving multidisciplinary teams driving projects from discovery through IND, with opportunities to grow alongside high-achieving teams.

What makes a strong candidate for this Senior Scientist position?

A strong candidate will have a Ph.D. in immunology, immuno-oncology, or tumor immunology, expertise in T cell immunology, experience designing novel assays, and excellent communication skills for collaboration.

Bristol-Myers Squibb

Develops and delivers biopharmaceutical medicines

About Bristol-Myers Squibb

Bristol Myers Squibb (BMS) develops and delivers medicines aimed at treating serious diseases, focusing on areas like cancer, autoimmune diseases, and heart conditions. The company conducts extensive research and development to create new drugs, which are sold after receiving regulatory approval. BMS also produces generic drugs, offering affordable alternatives that meet the same quality standards as their branded counterparts. What sets BMS apart from competitors is its dual focus on both innovative and generic medicines, enhancing access to healthcare. The company's goal is to improve patient outcomes while maintaining a commitment to sustainability and corporate responsibility.

New York City, New YorkHeadquarters

1887Year Founded

$33,706.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Flexible Work Hours

Hybrid Work Options

Professional Development Budget

Risks

Increased competition in oncology from emerging biotech firms like ArsenalBio.

BMS's lawsuit over the 340B Drug Pricing Program may lead to regulatory challenges.

Rapid AI and digital tech evolution may pose integration challenges for BMS.

Differentiation

BMS focuses on innovative cancer treatments through collaborations like ArsenalBio for T cell therapies.

The company emphasizes digital health technologies, enhancing clinical trial management and patient engagement.

BMS offers both innovative and generic medicines, increasing affordable healthcare solutions.

Upsides

BMS's partnership with Medidata enhances clinical research processes and patient outcomes.

The collaboration with AI Proteins advances novel miniprotein-based therapeutics, expanding therapeutic modalities.

BMS's global license agreement with BioArctic expands its portfolio in neurodegenerative diseases.

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