Scientist I/II/Senior Scientist, Medicinal Chemistry at Hexagon Bio

Menlo Park, California, United States

Hexagon Bio Logo
Not SpecifiedCompensation
Junior (1 to 2 years), Senior (5 to 8 years)Experience Level
Full TimeJob Type
UnknownVisa
Biotechnology, PharmaceuticalsIndustries

Requirements

  • Scientist I: Ph.D. in organic or medicinal chemistry, and 0+ years postdoctoral and/or industry experience
  • Scientist II: Ph.D. in organic or medicinal chemistry, and 2+ years postdoctoral and/or industry experience
  • Senior Scientist: Ph.D. in organic or medicinal chemistry, and 4+ years postdoctoral and/or industry experience
  • Ability to perform complex multistep synthesis quickly, efficiently, and safely
  • Ability to effectively summarize and communicate research findings
  • Ability to work full-time onsite at Menlo Park, CA laboratories

Responsibilities

  • Structure-based and hypothesis-driven design of new ADC payload and linker-payload drug compounds
  • Multistep synthesis, purification, and characterization of new ADC payload and linker-payload drug compounds
  • May manage aspects of a drug discovery program
  • May manage chemistry at a contract research organization

Skills

Key technologies and capabilities for this role

Medicinal ChemistryOrganic ChemistryMultistep SynthesisStructure-Based DesignPurificationCharacterizationDrug DiscoveryADC PayloadsLinker-Payload Compounds

Questions & Answers

Common questions about this position

What is the salary range for this position?

The salary range for this position is $120,000 - $180,000, dependent on the level of experience.

Is this role remote or onsite?

This role requires the ability to work full-time onsite at Menlo Park, CA laboratories.

What are the key requirements for this medicinal chemistry role?

A Ph.D. in organic or medicinal chemistry is required, with varying postdoctoral and/or industry experience depending on the level: 0+ years for Scientist I, 2+ years for Scientist II, and 4+ years for Senior Scientist. Candidates must also demonstrate ability to perform complex multistep synthesis quickly, efficiently, and safely, and effectively summarize and communicate research findings.

What is the company culture like at Hexagon Bio?

Hexagon Bio offers a flexible and dynamic work environment that cultivates unique strengths, provides mobility across departments, and fosters collaboration, curiosity, and open communication through All Hands Meetings, team-building events like happy hours and holiday parties.

What makes a strong candidate for this Scientist position?

Strong candidates will have a Ph.D. in organic or medicinal chemistry with relevant postdoctoral or industry experience matching the level, proven ability to perform complex multistep synthesis efficiently and safely, and skills in summarizing and communicating research findings effectively.

Hexagon Bio

Biotechnology firm developing medicines using genomics

About Hexagon Bio

Hexagon Bio specializes in discovering and developing new medicines using synthetic biology and data science. They analyze genomic data from various species to identify small molecule inhibitors that target proteins involved in diseases like cancer. Their unique platform allows for rapid production of lead compounds, enabling faster clinical development compared to traditional methods. The company's goal is to create effective treatments for complex diseases and license their drug candidates to larger pharmaceutical companies.

Menlo Park, CaliforniaHeadquarters
2016Year Founded
$178.6MTotal Funding
LATE_VCCompany Stage
Biotechnology, HealthcareIndustries
51-200Employees

Benefits

Flexible Work Hours
Gym Membership

Risks

Faces competition from biotech companies like Insitro and Recursion Pharmaceuticals.
Requires continuous updates to their platform due to rapid technological advancements.
Relies on external funding, posing financial risks if future funding is scarce.

Differentiation

Hexagon Bio uses synthetic biology to discover drugs from fungal genomes.
Their proprietary platform combines data science and synthetic biology for drug discovery.
Hexagon Bio's team includes experts in computational biology, biochemistry, and software engineering.

Upsides

Raised $77.3 million in Series B financing to expand their discovery platform.
Leverages reduced DNA sequencing costs to access vast genomic data.
Partnerships in AI and machine learning enhance drug discovery efficiency.

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