Medical Director, Clinical Development

Position Overview

• Location Type: Hybrid – Waltham, MA (In-office 3 days/week, Remote considered)
• Job Type: Full-time
• Salary: Not specified

Job Title: Medical Director, Clinical Development

Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka’s mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. We have raised nearly $500M since inception in February 2024 from top-tier investors and our first program is expected to be in the clinic in the first quarter of 2025. For more information, visit www.orukatx.com.

Requirements

• Not specified

Responsibilities

Clinical Trial Design and Oversight:

• Supports the development of clinical trial protocols, including patient selection criteria, study endpoints, and data collection methods.
• Oversees the conduct of clinical trials at study sites, ensuring adherence to protocols and good clinical practice (GCP) guidelines.
• Reviews and interprets clinical data to assess the safety and efficacy of the investigational drug.
• Authors and contributes to clinical and non-clinical documents required during the clinical development process (including but not limited to: Clinical Study Protocols, Investigator Brochures, Clinical Study Reports).

Medical Expertise:

• Provides medical expertise of the therapeutic area, disease state, and potential drug effects.
• Reviews clinical data to identify and analyze safety concerns and adverse events, and makes appropriate recommendations to the team.
• Stays current with relevant scientific literature and regulatory guidelines.

Company Information

Oruka Therapeutics (Nasdaq: ORKA) is a biopharmaceutical company focused on developing novel biologics for chronic skin diseases. They have raised nearly $500M since inception and expect their first program to be in the clinic in Q1 2025. They are building a company culture focused on engagement, inclusion, and positivity.