Responsibilities

The Research Engineer will develop and optimize high-throughput in vitro protein characterization assays, including binding, stability, solubility, and enzymatic activity assays. They will design and automate cell-based assays for functional protein characterization, including reporter assays, cell surface binding, internalization assays, and proliferation or signaling assays. The role involves automating assay workflows using liquid handlers, robotic platforms, and microfluidics to scale up experimental throughput and reproducibility. The engineer will develop multiplexed and miniaturized screening approaches, integrating NGS-based functional screening and microfluidic-based selection for protein engineering applications. They will work closely with the Software and ML Teams to integrate assay data into computational pipelines for real-time analysis and predictive modeling. Additionally, the engineer will analyze and interpret large datasets, applying statistical methods and machine learning to extract biological insights, and optimize assays for library screening and directed evolution to support protein optimization efforts with high-throughput functional readouts.