Senior Scientist, Process Development at Gilead Sciences

Edmonton, Alberta, Canada

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, BiotechnologyIndustries

Requirements

PhD in Organic Chemistry (or related discipline) and 2+ years of relevant experience (preferred 2-10 years), or MSc/BSc with 6-8+ years of extensive industry experience
Experience in planning and executing multi-step synthesis of organic molecules
Experience scaling up synthetic routes and developing safe processes
Familiarity with purification and analytical techniques, including HPLC, LCMS, and NMR
Familiarity with pilot plant and/or plant operations, and experience with generating master batch records (asset)
Familiarity with process validation, regulatory filings, and cGMP regulatory guidelines (asset)
Strong desire to work in multi-disciplinary teams, learn new skills, and solve problems
Excellent verbal and written communication skills, and strong interpersonal collaboration skills
Ability to think critically and creatively, work independently, and determine appropriate resources for problem resolution
Strong organizational and planning skills
Experience with project and people management (asset)

Responsibilities

Develop chemical processes for the manufacturing of drug substances
Demonstrate technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for novel chemical substances
Plan, execute, and analyze laboratory experimentation to advance knowledge of production and quality attributes of drug substances
Propose alternative chemistry, including new route selection and step optimization
Provide regular updates to supervision and propose future research directions
In collaboration with senior scientists, develop project strategy for manufacturing of drug substances to support clinical studies and commercialization
Manage day-to-day project team members and research assignments, including designing and interpreting experimentation
Prepare and review technical documents including research reports, process development reports, and documentation for manufacturing (e.g., Master Batch Records)
Collaborate across functional areas (analytical chemistry, quality assurance, manufacturing) to accomplish project goals; act as subject matter expert
Provide technical support for cGMP manufacturing processes in laboratory and large-scale operations
Ensure experimentation follows SOPs, maintaining quality, safety, and environmental standards

Skills

chemical process development

drug substance manufacturing

laboratory experimentation

route selection

step optimization

analytical chemistry

Gilead Sciences

Develops and commercializes biopharmaceuticals

About Gilead Sciences

Gilead Sciences focuses on discovering, developing, and commercializing medicines for various medical conditions, including HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular issues. The company conducts extensive research and development to create new therapies, which are then marketed to healthcare providers, hospitals, and pharmacies after receiving regulatory approval. Gilead differentiates itself from competitors through its strong commitment to R&D and strategic partnerships, such as with SAP Ariba, to enhance its operations and product offerings. The company's goal is to improve health equity and access to care globally, working with communities to ensure that its medicines reach those in need.

Foster City, CaliforniaHeadquarters

1987Year Founded

$15,873.6MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Paid family time off and paid parental time off

Generous 401(k) contribution matching

Comprehensive medical plans that cover both physical and mental healthcare

Global Wellbeing Reimbursement

Time Off

Global Volunteer Day

Giving Together Program

Employee Support Programs

Flexible Work Options

Risks

Increased competition in HIV treatment from ViiV Healthcare's expanding drug portfolio.

Regulatory scrutiny over drug pricing could impact Gilead's U.S. market operations.

Patent expirations, like Truvada's, lead to increased generic competition and revenue loss.

Differentiation

Gilead's lenacapavir is recognized as the 2024 Breakthrough of the Year for HIV care.

Partnerships with LEO Pharma and Tubulis enhance Gilead's focus on inflammatory and cancer therapies.

Gilead's commitment to health equity initiatives like COMPASS and HepConnect sets it apart.

Upsides

Gilead's strategic partnerships expand its reach in inflammatory and oncology drug markets.

Investment in digital health technologies enhances Gilead's R&D and patient engagement.

Focus on sustainability improves Gilead's operational efficiency and corporate reputation.

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