Scientist, Biology at Gilead Sciences

Foster City, California, United States

Gilead Sciences Logo
Not SpecifiedCompensation
Mid-level (3 to 4 years), Senior (5 to 8 years)Experience Level
Full TimeJob Type
UnknownVisa
Pharmaceuticals, BiotechnologyIndustries

Requirements

  • Bachelor's Degree and 6 years experience OR Master's Degree and 4 years experience
  • Preferred: Ph.D. with a minimum of 2 years of experience, or an M.Sc. with 5-7 years of experience in biochemistry, enzymology, biophysics or a related scientific discipline
  • Preferred: Direct experience in assay development and/or inhibitor mechanism of action studies

Responsibilities

  • Apply steady-state and pre-steady-state kinetic assays to characterize enzyme targets and inhibitor mechanism of action
  • Experience with mass spectrometry-based and biosensor approaches for lead ID characterization of novel and traditional drug modalities including PROTACs, molecular glues and covalent inhibitors
  • Strong technical background in cellular assay development and signaling pathways
  • Be both a critical and creative thinker and be able to apply an advanced level of understanding and analytical skills to interpret data and draw conclusions within the broader context of project goals
  • Able to troubleshoot and optimize assays as needed, identifying, and applying novel techniques or proactively seeking out solutions
  • Perform critical experiments to enable hit identification and lead optimization across therapeutic modalities
  • Provide scientific insight and in-depth data interpretation to inform decision making at the project team and leadership levels
  • Evaluate and implement new technologies to support advancement of internal programs and core group functions
  • Contribute to several projects at any given time, work successfully in a cross-functional team environment, and communicate clearly both verbally and in writing to a variety of audiences

Skills

Key technologies and capabilities for this role

BiophysicsBiochemical AssaysBiophysical AssaysCellular AssaysDrug DiscoverySmall MoleculesBiologics

Questions & Answers

Common questions about this position

What specific technical skills are required for the Scientist, Biology position?

The role requires experience with steady-state and pre-steady-state kinetic assays to characterize enzyme targets and inhibitor mechanism of action, mass spectrometry-based and biosensor approaches for lead ID characterization of novel drug modalities including PROTACs, molecular glues and covalent inhibitors, and strong technical background in cellular assay development and signaling pathways.

What soft skills or attributes are needed for this role?

The candidate must be a critical and creative thinker with an advanced level of understanding and analytical skills to interpret data and draw conclusions in the context of project goals, able to troubleshoot and optimize assays, and work effectively across diverse functional groups in a highly matrixed organization.

Is this a remote position or does it require on-site work?

This information is not specified in the job description.

What is the salary or compensation for this Scientist, Biology role?

This information is not specified in the job description.

What kind of candidate stands out for this position?

A highly motivated and creative Research Scientist who can collaborate in multi-disciplinary teams, contribute to biophysics capabilities for drug candidate identification, and demonstrate strong troubleshooting skills in assay development will be a strong fit.

Gilead Sciences

Develops and commercializes biopharmaceuticals

About Gilead Sciences

Gilead Sciences focuses on discovering, developing, and commercializing medicines for various medical conditions, including HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular issues. The company conducts extensive research and development to create new therapies, which are then marketed to healthcare providers, hospitals, and pharmacies after receiving regulatory approval. Gilead differentiates itself from competitors through its strong commitment to R&D and strategic partnerships, such as with SAP Ariba, to enhance its operations and product offerings. The company's goal is to improve health equity and access to care globally, working with communities to ensure that its medicines reach those in need.

Foster City, CaliforniaHeadquarters
1987Year Founded
$15,873.6MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
10,001+Employees

Benefits

Paid family time off and paid parental time off
Generous 401(k) contribution matching
Comprehensive medical plans that cover both physical and mental healthcare
Global Wellbeing Reimbursement
Time Off
Global Volunteer Day
Giving Together Program
Employee Support Programs
Flexible Work Options

Risks

Increased competition in HIV treatment from ViiV Healthcare's expanding drug portfolio.
Regulatory scrutiny over drug pricing could impact Gilead's U.S. market operations.
Patent expirations, like Truvada's, lead to increased generic competition and revenue loss.

Differentiation

Gilead's lenacapavir is recognized as the 2024 Breakthrough of the Year for HIV care.
Partnerships with LEO Pharma and Tubulis enhance Gilead's focus on inflammatory and cancer therapies.
Gilead's commitment to health equity initiatives like COMPASS and HepConnect sets it apart.

Upsides

Gilead's strategic partnerships expand its reach in inflammatory and oncology drug markets.
Investment in digital health technologies enhances Gilead's R&D and patient engagement.
Focus on sustainability improves Gilead's operational efficiency and corporate reputation.

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