Scientist, Biology at Gilead Sciences

Foster City, California, United States

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Not SpecifiedCompensation

Mid-level (3 to 4 years), Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, BiotechnologyIndustries

Requirements

Bachelor's Degree and 6 years experience OR Master's Degree and 4 years experience
Preferred: Ph.D. with a minimum of 2 years of experience, or an M.Sc. with 5-7 years of experience in biochemistry, enzymology, biophysics or a related scientific discipline
Preferred: Direct experience in assay development and/or inhibitor mechanism of action studies

Responsibilities

Apply steady-state and pre-steady-state kinetic assays to characterize enzyme targets and inhibitor mechanism of action
Experience with mass spectrometry-based and biosensor approaches for lead ID characterization of novel and traditional drug modalities including PROTACs, molecular glues and covalent inhibitors
Strong technical background in cellular assay development and signaling pathways
Be both a critical and creative thinker and be able to apply an advanced level of understanding and analytical skills to interpret data and draw conclusions within the broader context of project goals
Able to troubleshoot and optimize assays as needed, identifying, and applying novel techniques or proactively seeking out solutions
Perform critical experiments to enable hit identification and lead optimization across therapeutic modalities
Provide scientific insight and in-depth data interpretation to inform decision making at the project team and leadership levels
Evaluate and implement new technologies to support advancement of internal programs and core group functions
Contribute to several projects at any given time, work successfully in a cross-functional team environment, and communicate clearly both verbally and in writing to a variety of audiences

Skills

Biophysics

Biochemical Assays

Biophysical Assays

Cellular Assays

Drug Discovery

Small Molecules

Biologics

Gilead Sciences

Develops and commercializes biopharmaceuticals

About Gilead Sciences

Gilead Sciences focuses on discovering, developing, and commercializing medicines for various medical conditions, including HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular issues. The company conducts extensive research and development to create new therapies, which are then marketed to healthcare providers, hospitals, and pharmacies after receiving regulatory approval. Gilead differentiates itself from competitors through its strong commitment to R&D and strategic partnerships, such as with SAP Ariba, to enhance its operations and product offerings. The company's goal is to improve health equity and access to care globally, working with communities to ensure that its medicines reach those in need.

Foster City, CaliforniaHeadquarters

1987Year Founded

$15,873.6MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Paid family time off and paid parental time off

Generous 401(k) contribution matching

Comprehensive medical plans that cover both physical and mental healthcare

Global Wellbeing Reimbursement

Time Off

Global Volunteer Day

Giving Together Program

Employee Support Programs

Flexible Work Options

Risks

Increased competition in HIV treatment from ViiV Healthcare's expanding drug portfolio.

Regulatory scrutiny over drug pricing could impact Gilead's U.S. market operations.

Patent expirations, like Truvada's, lead to increased generic competition and revenue loss.

Differentiation

Gilead's lenacapavir is recognized as the 2024 Breakthrough of the Year for HIV care.

Partnerships with LEO Pharma and Tubulis enhance Gilead's focus on inflammatory and cancer therapies.

Gilead's commitment to health equity initiatives like COMPASS and HepConnect sets it apart.

Upsides

Gilead's strategic partnerships expand its reach in inflammatory and oncology drug markets.

Investment in digital health technologies enhances Gilead's R&D and patient engagement.

Focus on sustainability improves Gilead's operational efficiency and corporate reputation.

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