Research Associate II / Senior Research Associate at Tr1X

San Diego, California, United States

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Not SpecifiedCompensation

Junior (1 to 2 years), Mid-level (3 to 4 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Cell TherapyIndustries

Requirements

Bachelor’s degree in immunology, cell biology or a related scientific field
Minimum 2+ years (Research Associate II) or 4+ years (Senior Research Associate) of industry or equivalent experience in assay development in immunology, cell biology, or a related field, ideally within a translational or biomarker-focused setting
Proficiency in flow cytometry–based assays including panel design, sample processing, instrument setup, data acquisition, data analysis, and troubleshooting
Hands-on experience in maintaining cell cultures and executing cell-based assays
Demonstrated ability to reproducibly conduct multiplex immune-assays (e.g., ELISA, MSD) and/or molecular assays
Proficiency with analytical software programs (Prism, FlowJo, etc)
Strong attention to detail with the ability to follow SOPs and maintain real-time, accurate documentation in ELNs
Familiarity with assay development, qualification, and validation workflows, and knowledge of GxP principles or compliance expectations relevant to clinical sample handling and processing, is a plus
Ability to prepare clear experimental summaries (design and data) and deliver oral presentations
Proven ability to manage multiple tasks (inferred from context)

Responsibilities

Process human blood and tissue samples according to SOPs and established workflows
Perform weekly flow cytometry runs, including sample preparation, instrument setup (QC, compensation, PMT adjustments), data acquisition, and troubleshooting
Complete and deliver real-time data analysis ensuring accuracy, reproducibility, and adherence to assay requirements
Conduct MSD/ELISA and molecular assays (e.g., dPCR) as needed
Maintain cell cultures and perform cell-based assays
Support assay development, optimization, qualification, and troubleshooting in collaboration with scientists
Prepare concise summaries of experimental design and results; deliver presentations in team settings
Ensure accurate, real-time documentation of all activities using an electronic lab notebook (ELN)
Contribute to SOP drafting, updates, method documentation, and controlled form revisions
Participate in clinical sample management including receipt, logging, storage, aliquoting, and preparation for downstream analyses
Maintain detailed documentation, chain-of-custody, and compliance expectations for clinical samples
Perform routine lab upkeep such as reagent inventory
Perform other responsibilities based on business needs

Skills

flow cytometry

sample preparation

data acquisition

ELISA

MSD

dPCR

cell culture

cell-based assays

SOPs

molecular assays

Tr1X

Develops cellular immunotherapies for autoimmune diseases

About Tr1X

Tr1X focuses on developing cellular immunotherapies aimed at treating autoimmune and inflammatory diseases. The company uses a proprietary platform to create cell therapy products that help to rebalance the immune system and restore its natural balance, which is essential for long-term health. Unlike many other companies in the biopharmaceutical sector, Tr1X specializes in first-in-class therapies that target the underlying causes of immune system disorders rather than just alleviating symptoms. The goal of Tr1X is to provide advanced therapeutic solutions that lead to lasting tolerance in patients, improving their quality of life.

San Diego, CaliforniaHeadquarters

2018Year Founded

$73MTotal Funding

SERIES_ACompany Stage

Biotechnology, HealthcareIndustries

11-50Employees

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

Unlimited Paid Time Off

401(k) Company Match

Flexible Work Hours

Stock Options

Performance Bonus

Risks

Emerging competition in allogeneic Treg therapy could impact Tr1X's market share.

High manufacturing costs may pose financial risks for Tr1X.

Regulatory hurdles could delay Tr1X's product development and market entry.

Differentiation

Tr1X uses a proprietary platform for novel cellular immunotherapies.

The company focuses on allogeneic regulatory T-cell therapies for autoimmune diseases.

Tr1X's TRX103 is the first allogeneic engineered Tr1 regulatory T cell product.

Upsides

FDA clearance for TRX103 IND boosts Tr1X's credibility and market potential.

$75M Series A funding supports rapid development of Tr1X's therapies.

Growing autoimmune therapeutics market offers significant opportunities for Tr1X's products.

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