Axsome Therapeutics Inc

Machine Learning Scientist II/Sr (Biomedical Images) - UK

United Kingdom

Not SpecifiedCompensation
Junior (1 to 2 years), Senior (5 to 8 years)Experience Level
Full TimeJob Type
UnknownVisa
Biotechnology, Pharmaceuticals, Biomedical EngineeringIndustries

Machine Learning Scientist II / Senior

Employment Type: Full-Time Location Type: Remote Salary: [Not Specified]

Position Overview

Iambic Therapeutics is seeking a Machine Learning Scientist II or Senior to enhance its Enchant platform by integrating clinically relevant imaging. The successful candidate will be responsible for designing and building models that leverage medical images and multimodal biomedical data to advance drug discovery and clinical decision-making. This is a remote position, with a preference for candidates located in Bristol.

Key Responsibilities

  • Evaluate, adapt, and integrate pre-trained computer-vision models (e.g., Vision Transformers, vector-quantized encoders) into Enchant's existing modalities.
  • Locate and curate clinical imaging datasets (radiology, pathology, microscopy, etc.) and establish clear benchmarks for model performance.
  • Build robust data pipelines for large image collections, encompassing ingestion, preprocessing, augmentation, and storage.
  • Transition research prototypes into production services on multi-GPU/HPC infrastructure and ensure their ongoing maintenance.
  • Collaborate with discovery, pre-clinical, and clinical teams to translate image insights into experimental and trial strategies.
  • Disseminate findings through code, documentation, and internal presentations; mentor colleagues in vision and multimodal ML.

Required Qualifications

  • PhD with 3+ years of industry experience, or MS with 5+ years of industry experience, in Computer Vision, Machine Learning, Biomedical Engineering, or a related field.
  • Solid experience with deep learning for images, including self-supervised pre-training, Vision Transformers, or vector quantization methods.
  • Hands-on experience with large medical or scientific imaging datasets, including the establishment of evaluation tasks and metrics.
  • Proficiency in PyTorch or JAX and experience with distributed training on GPUs or cloud HPC resources.
  • Strong software engineering practices: version control, testing, continuous integration, code review, and containerization.
  • Excellent communication skills and the ability to collaborate effectively in cross-disciplinary teams.

Preferred Qualifications

  • Familiarity with multimodal transformers.
  • Experience aligning image embeddings with molecular or clinical endpoints.
  • Contributions to open-source computer-vision or ML projects.

About Iambic Therapeutics

Iambic is a clinical-stage life-science and technology company dedicated to developing novel medicines through its AI-driven discovery and development platform. Founded in 2020 and based in San Diego, Iambic has assembled a world-class team comprising pioneering AI experts and seasoned drug hunters. The Iambic platform has a proven track record of delivering new drug candidates to human clinical trials with exceptional speed across various target classes and mechanisms of action. Iambic is actively advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and through partnerships, to address urgent unmet patient needs. More information about the Iambic team, platform, pipeline, and partnerships can be found at iambic.ai.

Mission & Core Values

Iambic's mission is to deliver better medicines through innovations in AI-based discovery technologies. The company's culture and work are significantly enriched by the diversity of its people, including their backgrounds, cultures, national origins, religions, sexual orientations, and life experiences. Iambic is committed to fostering an inclusive environment where a diverse group of talented individuals collaborate to discover therapeutics and create cutting-edge technologies.

Pay and Benefits

Iambic Therapeutics offers a competitive compensation package, pension contributions, and flexible holiday allowances. The UK office provides a modern and collaborative work environment located in the heart of Bristol.

Application Instructions

[Not Specified]

Skills

Deep Learning
Computer Vision
Vision Transformers
Vector Quantization
PyTorch
JAX
Distributed GPU Training
Medical Imaging
Data Pipelines
Model Deployment
Multimodal ML

Axsome Therapeutics Inc

Develops therapies for CNS disorders

About Axsome Therapeutics Inc

Axsome Therapeutics develops therapies for central nervous system (CNS) disorders, focusing on conditions like major depressive disorder, treatment-resistant depression, and Alzheimer's agitation. Their main product, AXS-05, is an oral medication that works by blocking NMDA receptors in the brain, which helps regulate mood. This drug has shown positive results in clinical trials and has received special FDA status to speed up its approval process. Unlike many competitors, Axsome emphasizes addressing unmet medical needs in CNS disorders and aims to improve patient outcomes through rigorous research and development. The company's goal is to bring effective treatments to market, enhancing the quality of life for patients suffering from these conditions.

New York City, New YorkHeadquarters
2012Year Founded
$430.7MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
201-500Employees

Benefits

Performance Bonus
Company Equity

Risks

Increased competition from companies like Compass Pathways in the CNS market.
Potential delays in AXS-07 launch amid growing market anticipation.
Departure of key personnel like Lori Englebert may impact strategic direction.

Differentiation

Axsome focuses on CNS disorders with limited current treatment options.
AXS-05, an NMDA receptor antagonist, targets major depressive disorder and treatment-resistant depression.
Axsome's balanced portfolio includes both clinical and research stage products.

Upsides

FDA's fast-tracking of CNS treatments could expedite Axsome's drug approvals.
Increased investment in CNS R&D drives innovation, benefiting Axsome's pipeline.
Growing personalized medicine trend offers Axsome opportunities for tailored therapies.

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