Head of Biotherapeutics (Sr. Director or VP Level) at Manifold Bio

Boston, Massachusetts, United States

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Not SpecifiedCompensation

Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

BiotechnologyIndustries

Requirements

Experience taking multiple molecules through IND and into the clinic
Deep understanding of protein production techniques, including mammalian cell culture and purification/characterization approaches
Expertise in novel biotherapeutic modalities, across a range of formats
Extensive experience leading cross-functional teams
Experience with complex biologics (e.g. multispecifics)
Preferred Qualifications
Experience with drug development in neuroscience
Experience liaising with CDMOs through IND
Experience with generative AI models for protein design

Responsibilities

Leading internal protein sciences and protein engineering teams
Own strategy for early stage de-risking and optimization of lead molecules
Own strategy for developability assessment
Work with internal and external team members to ensure cost-effective and timely drug manufacture
Build internal expertise on cutting-edge protein engineering techniques
Guide prioritization for internal protein generation efforts, balancing between screening and lead characterization
Build an R&D-to-development pipeline for lead candidates
Utilize state of the art techniques to drive the development of best-in-class therapeutic candidates
Stay up to speed on cutting edge research and industry standards for protein therapeutics

Skills

Protein Engineering

Biologics Manufacturing

CMC

IND

High-Throughput Screening

Protein Production

Computational Design

Antibody Engineering

Manifold Bio

Designs precision biologics using in vivo methods

About Manifold Bio

Manifold Bio specializes in creating precision biologics for the pharmaceutical industry, focusing on drug design and development. Their main product is an in vivo drug design platform, which allows for testing drugs within living organisms rather than in laboratory settings. This platform utilizes mCodes™ technology, a unique protein barcoding system that enables the simultaneous study of multiple proteins in one experiment, making it particularly effective for complex biologics. Unlike other companies, Manifold Bio's approach to drug design is distinct because it integrates in vivo testing with advanced protein multiplexing capabilities. The company's goal is to expand their platform and collaborate with other pharmaceutical companies to develop new therapeutics.

Boston, MassachusettsHeadquarters

2020Year Founded

$58.8MTotal Funding

SERIES_ACompany Stage

Biotechnology, HealthcareIndustries

11-50Employees