Associate Research Scientist at Bristol-Myers Squibb

Seattle, Washington, United States

Bristol-Myers Squibb Logo
Not SpecifiedCompensation
Junior (1 to 2 years), Mid-level (3 to 4 years)Experience Level
Full TimeJob Type
UnknownVisa
Biotechnology, PharmaceuticalsIndustries

Requirements

  • B.S. with 4+ years or M.S. with 2+ years of hands-on experience in flow cytometry method development, validation, sample testing, and data analysis (prior industry experience preferred)
  • 3+ years experience in cell therapy drug product characterization including both allogeneic and autologous programs (strongly preferred)
  • Strong understanding of method validation guidelines and GxP laboratory procedures
  • Previous experience in an analytical development or QC laboratory (strongly preferred)
  • Proficiency in acquisition, analysis, and interpretation of flow cytometry data (experience with BD FACSLyric, FACSuite, FlowJo, FCS Express preferred)
  • Experience in executing method validation experiments
  • Able to independently perform flow cytometry panel design
  • Ability to design and perform experiments, and interpret results using statistical software (e.g., JMP/Excel)
  • Independently motivated with ability to multi-task, problem-solve, train team members on lab operations, and coordinate activities within a team
  • Desire and drive to learn the biological mechanism of cell and gene therapy products and passion for their impact on patients
  • Ability to communicate clearly and concisely through oral presentation and technical writing
  • Embrace BMS shared values of passion, innovation, urgency, accountability, inclusion, and integrity

Responsibilities

  • Work in the cellular phenotype group to support development, validation, and transfer of flow cytometry based analytical methods
  • Perform hands-on experimental work for development of flow cytometry analytical methods
  • Execute flow cytometry panels for detecting low level marker expression (e.g., knockouts, knockdown)
  • Support execution of phase appropriate validation and method transfer experiments designed to measure parameters such as precision, LLOQ, LOD, detection range, and repeatability
  • Support routine critical reagent qualification for method development, phase appropriate validations, and transfers
  • Support method optimization and robustness assays to test method reliability and performance
  • Support cell culturing and cell banking efforts
  • Support life cycle management activities
  • Maintain and organize LN2 storage space as needed
  • Maintain proper documentation of experimental results using an electronic lab notebook
  • Summarize, verify, and present scientific data; communicate progress to project teams
  • Author technical documents including protocols, development reports, and PAV/transfer reports
  • Follow lab safety rules and practices

Skills

flow cytometry
analytical methods
cell culturing
cell banking
method validation
method transfer
LLOQ
LOD
precision testing
electronic lab notebook
scientific data analysis

Bristol-Myers Squibb

Develops and delivers biopharmaceutical medicines

About Bristol-Myers Squibb

Bristol Myers Squibb (BMS) develops and delivers medicines aimed at treating serious diseases, focusing on areas like cancer, autoimmune diseases, and heart conditions. The company conducts extensive research and development to create new drugs, which are sold after receiving regulatory approval. BMS also produces generic drugs, offering affordable alternatives that meet the same quality standards as their branded counterparts. What sets BMS apart from competitors is its dual focus on both innovative and generic medicines, enhancing access to healthcare. The company's goal is to improve patient outcomes while maintaining a commitment to sustainability and corporate responsibility.

New York City, New YorkHeadquarters
1887Year Founded
$33,706.1MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
10,001+Employees

Benefits

Flexible Work Hours
Hybrid Work Options
Professional Development Budget

Risks

Increased competition in oncology from emerging biotech firms like ArsenalBio.
BMS's lawsuit over the 340B Drug Pricing Program may lead to regulatory challenges.
Rapid AI and digital tech evolution may pose integration challenges for BMS.

Differentiation

BMS focuses on innovative cancer treatments through collaborations like ArsenalBio for T cell therapies.
The company emphasizes digital health technologies, enhancing clinical trial management and patient engagement.
BMS offers both innovative and generic medicines, increasing affordable healthcare solutions.

Upsides

BMS's partnership with Medidata enhances clinical research processes and patient outcomes.
The collaboration with AI Proteins advances novel miniprotein-based therapeutics, expanding therapeutic modalities.
BMS's global license agreement with BioArctic expands its portfolio in neurodegenerative diseases.

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