Natera

Staff Software Engineer - Revenue Cycle Management

San Carlos, California, United States

Not SpecifiedCompensation
Senior (5 to 8 years)Experience Level
Full TimeJob Type
UnknownVisa
Healthcare, Medical Billing, Revenue Cycle ManagementIndustries

Staff Software Engineer - Healthcare Billing Automation

Position Overview

We are seeking a Staff Software Engineer with deep expertise in healthcare billing, reimbursement, and revenue cycle systems to develop intelligent tools and automation that support our end-to-end billing operations. This role sits at the intersection of machine learning, healthcare operations, and financial optimization.

You will work closely with our Billing, RCM, Data Engineering, and Compliance teams to identify opportunities for automation, build production-grade models, and deliver ML-powered insights that reduce denials, maximize collections, and improve operational efficiency.

Responsibilities

  • Develop and deploy AI/ML models for denial prediction, claim prioritization, and payer behavior analysis.
  • Use NLP and computer vision (OCR) to extract structured data from unstructured inputs (e.g., paper faxes, remittance files, EOBs).
  • Build automated pipelines to monitor open accounts receivable (A/R) and generate exception reports.
  • Support optimization of CPT/ICD-10 coding accuracy using ML classifiers and claim outcome modeling.
  • Collaborate with Billing and RCM teams to identify gaps in collections, trends in denials, and areas for automation.
  • Create dashboards and tools to support reimbursement forecasting, financial performance reporting, and compliance audits.
  • Work with Compliance and Privacy teams to ensure HIPAA-compliant handling of PHI in all data pipelines.
  • Contribute to ongoing automation efforts to improve workflow efficiency across the billing cycle.

Requirements

Must-Have Qualifications

  • 5+ years of experience in AI/ML engineering with applied projects in healthcare, RCM, or medical billing.
  • Strong proficiency in Python, SQL, and ML libraries (scikit-learn, XGBoost, TensorFlow/PyTorch, etc.).
  • Experience with OCR/NLP tools such as Tesseract, AWS Textract, spaCy, or similar.
  • Proven track record building ML pipelines that integrate with backend systems or RPA tools.
  • Deep understanding of revenue cycle metrics: A/R aging, denial codes, CPT/HCPCS/ICD-10, claim statuses.
  • Experience working with EHR, clearinghouse, or payer data (e.g., 837/835 formats, ERA/EOBs).
  • Strong problem-solving and communication skills with a product and outcome-driven mindset.
  • Understanding of HIPAA and data privacy/security best practices for handling PHI.

Preferred Qualifications

  • Experience working with medical billing platforms (Waystar, eClinicalWorks, Epic, Cerner, etc.).
  • Familiarity with financial forecasting, bad debt analysis, and payer reimbursement models.
  • Background in bioinformatics, digital health, or clinical operations is a plus.
  • M.S. or Ph.D. in Computer Science, Data Science, Biomedical Informatics, or related field.

Compensation & Location

  • San Carlos, CA: $156,300 - $195,350 USD
  • Austin, TX: $136,300 - $170,400 USD

Note: The listed pay ranges are a guideline. Actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications, and specific office location. This may differ in other locations due to cost of labor considerations.

Company Information

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers, and many other professionals from world-class institutions, who care deeply for our work.

Skills

AI/ML Engineering
Healthcare Billing
Reimbursement
Revenue Cycle Management (RCM)
Python
SQL
scikit-learn
XGBoost
TensorFlow
PyTorch
OCR
NLP
Tesseract
AWS Textract
spaCy
ML Pipelines
RPA
HIPAA
CPT/ICD-10 coding
Denial Prediction
Claim Prioritization
Payer Behavior Analysis
Computer Vision

Natera

Genetic testing and diagnostics solutions provider

About Natera

Natera focuses on genetic testing and diagnostics, providing advanced solutions for cancer patients, transplant patients, and individuals assessing hereditary health risks. Their main technology is cell-free DNA (cfDNA) testing, which analyzes DNA fragments in the blood to detect minimal traces of cancer and assess organ health. Natera stands out by offering specialized tests like the Signatera ctDNA test and Panorama NIPT, along with genetic counseling services. The company's goal is to improve patient care and health outcomes through accurate genetic testing.

Austin, TexasHeadquarters
2004Year Founded
$149.9MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
1,001-5,000Employees

Benefits

Flexible medical plans
Investment options
Time off
Workplace perks

Risks

Hindenburg report accuses Natera of deceptive sales practices, risking legal challenges.
New Prospera Heart features may face slow adoption by healthcare providers.
Fetal RhD NIPT demand may drop post-RhIg shortage, affecting future sales.

Differentiation

Natera's Signatera test offers personalized ctDNA analysis for cancer patients.
Prospera Heart test uses unique Donor Quantity Score for transplant rejection detection.
Panorama NIPT test is a leader in non-invasive prenatal testing with 2 million tests.

Upsides

Increased adoption of liquid biopsy techniques boosts demand for Natera's cfDNA tests.
AI integration enhances accuracy and speed of Natera's cfDNA analysis.
Growing personalized medicine trend aligns with Natera's customized genetic tests.

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