Sr. Principal Infrastructure Architect – Manufacturing & Quality Systems at Eli Lilly and Company

Indianapolis, Indiana, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, ManufacturingIndustries

Requirements

Bachelor's degree in Computer Science, Engineering, Information Systems, or related field
5+ years of experience architecting IT infrastructure in GMP-regulated pharmaceutical or advanced manufacturing environments
2+ years of working with MES, EWM/WMS, DCS, Industrial IoT networks, and S95 Level 2+ architectures
Excellent communication and executive influence skills
Strong analytical capabilities with a proven track record of solving complex operational technology challenges
Experience working in fast-paced, operationally critical environments with multiple stakeholders and competing priorities

Responsibilities

Develop and maintain infrastructure architecture roadmaps for IPM, IDAP, and IDM, aligned with Tech@Lilly strategy
Lead infrastructure readiness for the transition from PMX to PharmaSuite and other key MES modernization initiatives
Architect secure, validated networking, compute, storage, and virtualization platforms supporting MES, EWM/WMS, Quality Systems, and S95 Level 2+ solutions
Provide technical leadership and escalation support for complex operational and cybersecurity challenges
Ensure compliance with GMP, GxP, CSV, and data integrity standards
Lead major infrastructure deployments and modernization programs across all three manufacturing areas
Partner with operations, engineering, automation, cybersecurity, and global architecture teams to deliver scalable solutions

Skills

Key technologies and capabilities for this role

IT InfrastructureGMPGxPCSVMESPharmaSuiteNetworkingComputeStorageVirtualizationEWMWMSS95CybersecurityData Integrity

Questions & Answers

Common questions about this position

What are the basic qualifications for this Sr. Principal Infrastructure Architect role?

Candidates need a Bachelor's degree in Computer Science, Engineering, Information Systems, or related field, plus 5+ years of experience architecting IT infrastructure in GMP-regulated pharmaceutical or advanced manufacturing environments, and 2+ years working with MES, EWM/WMS, DCS, Industrial IoT networks, and S95 Level 2+ architectures.

What salary or compensation is offered for this position?

This information is not specified in the job description.

Is this role remote or does it require working on-site?

This information is not specified in the job description.

What is the company culture like at Eli Lilly?

Eli Lilly unites caring with discovery to make life better for people around the world, putting people first, giving best effort to work, and contributing to communities through philanthropy and volunteerism.

What makes a strong candidate for this infrastructure architect position?

Strong candidates demonstrate ability to lead multi-site infrastructure programs, influence executive technology decisions, possess excellent communication and executive influence skills, strong analytical capabilities, and experience solving complex operational technology challenges in fast-paced environments.

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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