Sr. Advisor / Scientific Director - Peptide Phage Display (San Diego, CA) at Eli Lilly and Company

San Diego, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

Ph.D. degree in chemistry, biochemistry, or molecular biology with a strong focus on peptides
3+ years of experience in a biotechnology/pharmaceutical company with demonstrated leadership in peptide discovery and a track record of advancing peptide-based therapeutics from concept to clinical development

Responsibilities

Spearhead the design and execution of next-generation peptide phage display (cloning and screening with multicyclic peptide scaffolds) through individual contribution, training, and close collaboration with a team of scientists
Lead peptide phage display screening projects and collaborate with cross-functional teams to accelerate development of cyclic peptide hits for therapeutic applications, including peptide drug conjugates and peptide radionuclide conjugates
Mentor junior scientists and effectively communicate progress to cross-functional partners within Biotechnology Discovery Research and across Discovery Chemistry, Genetic Medicines, Therapeutic Area Teams, Drug Disposition, Bioproduct Development, and Regulatory Affairs
Apply expertise in molecular biology, genetic engineering, and chemistry to build a robust multicyclic peptide phage display platform
Execute the multicyclic peptide phage display platform for discovery and optimization of peptide hits for biological targets of interest
Develop new methods and technologies to strengthen the platform
Train junior scientists on building and executing the multicyclic peptide phage display platform
Lead screening projects and collaborate with experts in organic chemistry, computational science, and structural biology
Incorporate knowledge to improve peptide properties such as binding affinity or physicochemical properties
Collaborate with peptide chemists to implement rational SAR strategies to improve pharmaceutical properties of therapeutic peptide leads
Exhibit strong problem-solving abilities and resolve issues at the interface of peptide discovery, peptide engineering, pharmaceutical developability, formulation, and biology

Skills

Key technologies and capabilities for this role

Peptide Phage DisplayMolecular BiologyGenetic EngineeringChemistryCloningScreeningMulticyclic Peptide ScaffoldsPeptide Drug Conjugates

Questions & Answers

Common questions about this position

What is the location for this position?

The role is based in San Diego, CA.

What is the salary range for this role?

This information is not specified in the job description.

What qualifications are required for this position?

A Ph.D. degree in chemistry, biochemistry, or molecular biology with a strong focus on peptides is required.

What key skills and expertise are needed for this role?

Expertise in molecular biology, genetic engineering, chemistry, peptide phage display, and problem-solving abilities at the interface of peptide discovery, engineering, developability, and biology are essential.

What does the company culture emphasize?

Lilly unites caring with discovery to make life better for people, puts people first, and encourages giving back through philanthropy and volunteerism.

What makes a strong candidate for this position?

A candidate with a Ph.D. in chemistry, biochemistry, or molecular biology focused on peptides, expertise in multicyclic peptide phage display, strong problem-solving skills, and experience mentoring junior scientists stands out.

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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