Senior Scientist, iPSC Core Lead at Conception

Berkeley, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Reproductive BiologyIndustries

Requirements

PhD in Cell or Developmental Biology or related field (preferred), or Master’s with relevant industry experience
Extensive, senior-scientist-level experience with iPSC culture, naïve pluripotency (preferred), and differentiation protocols to one or more lineages
Proven ability to run organized, traceable, high-quality cell culture operations
Experience mentoring or managing junior scientists
Exceptionally organized, detail-oriented, and proactive
Strong communicator and collaborator
Motivation to build systems that scale from R&D to preclinical and CMC readiness
PhD or equivalent work experience

Responsibilities

Organize and run the iPSC core day-to-day
Maintain cell banks and execute QC for iPSCs and feeder lines
Track QC results, reagents, lots, consumables, and equipment; manage incubators and hoods in collaboration with Operations
Work closely with Operations to ensure differentiation protocols remain extremely stable and repeatable
Build and document SOPs for routine workflows
Collaborate with the Cell Engineering team to validate, QC, bank, and integrate new cell lines into the core
Establish strong communication loops with R&D teams to manage cell handoffs, define acceptance criteria, and communicate disruptions or delays to maintain quality
Lead, mentor, and grow a small team; set expectations for consistency, documentation, and accountability
Keep junior scientists engaged and motivated on core work; invest in training and mentorship
Coordinate across R&D and Operations to communicate timings, risks, delays, and mitigations proactively
Collaborate with R&D scientists to standardize and scale directed differentiation of at least one lineage, expanding to multiple lines over time
Partner with ML and computational biology experts to explore automated imaging and RNAseq as predictors of long-term culture success
Develop and implement new QC methods for differentiations
Propose innovations to improve cell quality, efficiency, and early risk detection

Skills

Key technologies and capabilities for this role

iPSCstem cell cultureQCcell bankingfeeder linesdifferentiation protocolsSOPsML imagingsequencingteam leadership

Questions & Answers

Common questions about this position

What qualifications are required for the Senior Scientist, iPSC Core Lead role?

A PhD in Cell or Developmental Biology or related field is preferred, or a Master’s with relevant industry experience, along with extensive senior-scientist-level experience with iPSC culture, naïve pluripotency (preferred), and differentiation protocols to one or more lineages.

Is this a full-time position?

Yes, this is a full-time employment opportunity.

What does the role involve in terms of team leadership?

You will lead, mentor, and grow a small team, set expectations for consistency, documentation, and accountability, and keep junior scientists engaged through training and mentorship.

What salary or compensation does this position offer?

This information is not specified in the job description.

What makes a strong candidate for this iPSC Core Lead position?

Ideal candidates are motivated, independent, highly organized scientists with a PhD (preferred) and senior-level expertise in iPSC culture, pluripotency, and differentiation, who can own lab operations, lead teams, and drive QC innovations.

Conception

Biotech firm developing egg cells from blood

About Conception

Conception.bio focuses on improving fertility treatments through advanced biotechnology. The company has developed a method to create viable egg cells from blood samples by transforming induced pluripotent stem cells (iPSCs) into mature egg cells. This process allows women to extend their fertility, provides new options for couples facing infertility, and enables genetic screening of embryos to avoid hereditary diseases. Unlike other fertility treatment providers, Conception.bio directly serves individuals and couples, including same-sex male couples, with a unique approach to egg cell development. The goal is to lead the fertility treatment market by offering effective solutions that address the diverse needs of those seeking to conceive.

Berkeley, CaliforniaHeadquarters

2017Year Founded

$23MTotal Funding

SERIES_ACompany Stage

Biotechnology, HealthcareIndustries

51-200Employees

Benefits

Health Insurance

Company Equity

Flexible Work Hours

Risks

Ethical concerns about iPSCs may lead to public backlash and regulatory challenges.

Competition from companies like Dioseve could impact Conception's market share.

Legal challenges in iPSC and fertility treatment IP rights could arise.

Differentiation

Conception turns skin cells into viable human eggs, a groundbreaking fertility innovation.

Their technology offers fertility solutions for women, infertile couples, and same-sex male couples.

Conception's iPSC-based approach allows for genetic screening and potential disease prevention.

Upsides

Growing interest in genetic screening boosts demand for Conception's reproductive technologies.

Advancements in CRISPR enhance Conception's potential for genetic disease prevention.

Fertility treatment market growth presents significant opportunities for Conception's solutions.

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