Scientific Director - Sustainable Peptide Process Chemistry – SMDD at Eli Lilly and Company

Indianapolis, Indiana, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, Healthcare, BiotechnologyIndustries

Requirements

Expertise in peptide process chemistry, including excellence in multiple modes of peptide synthesis such as hybrid SPPS/LPPS chemistry
Experience leading teams of scientists in peptide route development
Ability to enable the design, development, and implementation of sustainable, innovative processes for complex peptide synthesis, with a focus on PFAS-free conditions
Knowledge of green chemistry and engineering solutions to improve the environmental footprint of peptide manufacturing and reduce Process Mass Intensity (PMI)
Familiarity with chromatography, mass spectrometry, optical spectroscopy, and peptide automation
Strong technical problem-solving ability and intrinsic motivation to succeed in team environments
Track record of innovative scientific research

Responsibilities

Lead a team of peptide chemists in designing and developing sustainable synthetic peptide processes
Provide oversight for multi-kg scale peptide process development at contract manufacturing organizations (CMOs) and lead internal development activities
Educate and mentor CMOs on best practices for greener peptide development and manufacturing
Present research findings at internal forums and external conferences; publish in high-quality, peer-reviewed journals
Communicate both the technical and business implications of research outcomes clearly and effectively
Apply expertise in Tag-Assisted Liquid-Phase Peptide Chemistry to enable scalable and efficient peptide synthesis

Skills

Peptide Process Chemistry

Sustainable Peptide Development

Process Development

Peptide Commercialization

Incretin Therapies

Synthetic Chemistry

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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