Postdoctoral Scientist – Fibrosis, Liver Disease at Gilead Sciences

Foster City, California, United States

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Not SpecifiedCompensation

InternshipExperience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

Ph.D. in biochemistry, molecular biology, immunology or related discipline
At least one first author paper published or accepted in a peer-reviewed journal
Proficiency in mammalian cell biology and biochemistry techniques
Excellent written, verbal, and interpersonal communication skills
Strong organizational skills
Preferred Qualifications
Broad hands-on expertise in cell biology, molecular biology, biochemistry and imaging techniques including in vitro cell-based functional assays, primary cell cultures, transfection/transduction techniques, CRISPR/Cas9, microscopy, flow cytometry, and other immunoassays
Hands-on experience with mouse models of disease

Responsibilities

Initiate and lead independent research projects to investigate pathogenic mechanisms in chronic fibrotic liver disease
Utilize Gilead’s rich single cell and spatial transcriptomic datasets as well as clinical datasets to uncover novel mechanisms driving fibrotic niche expansion
Use a combination of mouse genetic and pharmacology approaches to investigate key disease drivers and establish novel ex vivo models allowing for target identification and screening
With the support of a mentor, design, conduct, and analyze in vitro and in vivo experiments to drive research towards publication in a top-tier journal
Publish work in top-tier journals and present at scientific conferences
Work in a highly collaborative environment leveraging expertise and resources across multiple functional areas

Skills

Key technologies and capabilities for this role

FibrosisLiver DiseaseMASHPBCPSCPathogenic MechanismsTherapeutic TargetsInflammation Biology

Questions & Answers

Common questions about this position

What is the duration of this postdoctoral position?

This is a three-year postdoctoral training position at Gilead.

Is this position remote or does it require on-site work?

This information is not specified in the job description.

What skills or experience are required for this role?

The role requires the ability to initiate and lead independent research projects, utilize single cell and spatial transcriptomic datasets along with clinical datasets, and apply mouse genetic and pharmacology approaches to investigate disease drivers and develop ex vivo models.

What is the work environment like at Gilead for this role?

The role is embedded in a highly collaborative and resource-rich environment, offering access to world-class facilities and cross-functional expertise across Gilead’s research ecosystem.

What makes a strong candidate for this postdoctoral scientist position?

A passionate and driven scientist ready to spearhead an independent research project on chronic fibrotic liver disease, with the ability to design, conduct, and analyze in vitro and in vivo experiments leading to high-impact publications in top-tier journals.

Gilead Sciences

Develops and commercializes biopharmaceuticals

About Gilead Sciences

Gilead Sciences focuses on discovering, developing, and commercializing medicines for various medical conditions, including HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular issues. The company conducts extensive research and development to create new therapies, which are then marketed to healthcare providers, hospitals, and pharmacies after receiving regulatory approval. Gilead differentiates itself from competitors through its strong commitment to R&D and strategic partnerships, such as with SAP Ariba, to enhance its operations and product offerings. The company's goal is to improve health equity and access to care globally, working with communities to ensure that its medicines reach those in need.

Foster City, CaliforniaHeadquarters

1987Year Founded

$15,873.6MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Paid family time off and paid parental time off

Generous 401(k) contribution matching

Comprehensive medical plans that cover both physical and mental healthcare

Global Wellbeing Reimbursement

Time Off

Global Volunteer Day

Giving Together Program

Employee Support Programs

Flexible Work Options

Risks

Increased competition in HIV treatment from ViiV Healthcare's expanding drug portfolio.

Regulatory scrutiny over drug pricing could impact Gilead's U.S. market operations.

Patent expirations, like Truvada's, lead to increased generic competition and revenue loss.

Differentiation

Gilead's lenacapavir is recognized as the 2024 Breakthrough of the Year for HIV care.

Partnerships with LEO Pharma and Tubulis enhance Gilead's focus on inflammatory and cancer therapies.

Gilead's commitment to health equity initiatives like COMPASS and HepConnect sets it apart.

Upsides

Gilead's strategic partnerships expand its reach in inflammatory and oncology drug markets.

Investment in digital health technologies enhances Gilead's R&D and patient engagement.

Focus on sustainability improves Gilead's operational efficiency and corporate reputation.

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