Advisor/Sr. Advisor - Mass Spectrometry-based Biomarker Discovery - Neuroscience at Eli Lilly and Company

Boston, Massachusetts, United States

Eli Lilly and Company Logo
Not SpecifiedCompensation
Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level
Full TimeJob Type
UnknownVisa
Pharmaceuticals, Biotechnology, HealthcareIndustries

Requirements

  • PhD in Neuroscience, Biochemistry or a related scientific field
  • 5+ years of industry, academic, or postdoctoral experience in biomarker development
  • Recognized expertise in mass spectrometry-based assays for brain diseases
  • Deep understanding of mass spectrometry technology and instrumentation
  • Mass spectrometry-based assay development and validation for biomarker applications in clinical trials
  • Technically skilled to independently execute advanced mass spectrometry-based studies
  • Proven leadership in managing and mentoring biomarker research teams in academic or industry settings
  • Strong strategic thinking, problem-solving abilities, and ability to drive innovation in biomarker discovery
  • Excellent communication, collaboration, and negotiation skills to influence internal and external stakeholders
  • Demonstrated ability to translate scientific findings

Responsibilities

  • Development and validation of novel mass spectrometry-based assays for early- and late-phase clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders
  • Work with project team leads and mentor junior associates to design and execute in vitro experiments to support preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development
  • Assist with the planning and execution of method development, optimization, and sample analyses, working with internal and external partners to coordinate readouts for complex studies
  • Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses
  • Serve as a scientific and technical expert for in-house and outsourced biomarker discovery efforts, establishing experimental study design and analytical strategies
  • Collaborate cross-functionally with internal stakeholders (medical, operations, statistics, regulatory) and external partners (CROs, academic institutions) to ensure biomarker validation and successful integration into clinical programs
  • Communicate findings through presentations, publications, and strategic discussions, reinforcing Lilly’s leadership in biomarker innovation

Skills

Key technologies and capabilities for this role

Mass SpectrometryBiomarker DiscoveryAssay DevelopmentAssay ValidationProteomicsClinical TrialsNeuroscience Biomarkers

Questions & Answers

Common questions about this position

What is the location for this role?

The role will be situated at Lilly’s research facilities in Boston.

What salary or compensation does this position offer?

This information is not specified in the job description.

What expertise is required for this position?

The role requires exceptional expertise in biomarker discovery with a demonstrated track record in mass spectrometry-based methodologies, along with skills in assay development, validation, and cross-functional collaboration.

What is the team structure like for this role?

The role is within a newly established team led by Dr. Kaj Blennow, Vice President of Neuroscience Biomarker Development, involving work with project team leads and mentoring junior associates.

What makes a strong candidate for this Advisor/Sr. Advisor role?

A strong candidate will have exceptional expertise in mass spectrometry-based biomarker discovery, a track record in neurodegenerative diseases, and experience guiding strategic direction and technical execution for clinical trials.

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters
1876Year Founded
$1,180.1MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.
Potential construction delays in Indiana could affect GLP-1 drug production timelines.
Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.
Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.
FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.
Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.
Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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