Sr Staff Scientist at Element Biosciences

San Diego, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Life SciencesIndustries

Requirements

Ph.D. in Biochemistry, Molecular Biology, Chemical Biology, or a related field, with 7+ years of postdoctoral or industry experience in molecular assay or reagent development
Strong background in nucleic acid and/or protein biochemistry, particularly in tissue-based or in situ assays
Demonstrated experience developing and optimizing reagents or workflows for biological assay products
Hands-on experience with tissue sample preparation, in situ hybridization, immunostaining, or enzymatic labeling
Industry experience in tissue-based product development, including reagent formulation, sample and workflow optimization, and validation
Experience with NGS-based readouts, multiomic workflows, or image-based molecular detection
Knowledge of design controls, assay verification, or manufacturing transfer processes
Strong record of innovation demonstrated by patents, publications, or successful product contributions
Proven ability to design experiments, analyze data, and troubleshoot complex biochemical systems
Proficiency in computational analysis for biological datasets using Python, R, or MATLAB
Excellent written and verbal communication skills, and ability to collaborate effectively in multidisciplinary teams
Ability to lift up to 20 pounds

Responsibilities

Design, develop, and optimize biochemical workflows and reagents for tissue-based multiomic applications
Design, conduct, analyze, and report on assays for developing workflows including in tissue sample sequencing of RNA, protein detection, and morphology
Integrate and test new chemistries and enzymatic methods to improve assay performance, robustness, and reproducibility
Contribute to product-oriented development efforts, including reagent stability, scalability, and manufacturability
Collaborate cross-functionally with hardware, chemistry, and software teams to ensure workflow compatibility with Element’s sequencing platforms
Analyze complex datasets and contribute to data interpretation and workflow optimization using coding and computational tools
Prepare detailed documentation, present findings to project teams and leadership, and contribute to publications and intellectual property filings

Skills

Key technologies and capabilities for this role

BiochemistryMolecular BiologyAssay DevelopmentRNA SequencingProtein DetectionMultiomicsWorkflow OptimizationReagent FormulationEnzymatic MethodsTissue AnalysisReagent StabilityScalability

Questions & Answers

Common questions about this position

What is the work arrangement for this role?

This is an onsite role at the company's San Diego headquarters.

What education and experience are required for this position?

A Ph.D. in Biochemistry, Molecular Biology, Chemical Biology, or a related field is required, along with 7+ years of postdoctoral or industry experience in molecular assay or reagent development. Candidates need a strong background in nucleic acid and/or protein biochemistry, particularly in tissue-based or in situ assays, hands-on experience with tissue sample preparation, in situ hybridization, immunostaining, or enzymatic labeling, and industry experience in tissue-based product development.

What does the company culture look like?

Element Biosciences has built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment, with commitments to scientific integrity, collegiality, honesty, objectivity, and openness.

What is the salary range for this Senior Staff Scientist role?

This information is not specified in the job description.

What makes a strong candidate for this role?

Strong candidates possess a Ph.D. with 7+ years of experience in molecular assay or reagent development, hands-on expertise in tissue-based assays like in situ hybridization and immunostaining, and industry experience in product development including reagent formulation and workflow optimization.

Element Biosciences

Next-generation sequencing technology provider

About Element Biosciences

Element Biosciences focuses on next-generation sequencing (NGS) technology, offering the AVITI System, a compact benchtop device that provides high-quality sequencing at a low cost of $1 per million reads. This system is designed for various clients, including academic researchers and pharmaceutical companies, and delivers industry-leading accuracy. Element Biosciences stands out by partnering with other biotech firms, like QIAGEN, to provide complete NGS workflows and by offering the 2023 AVITI for All Grant, which gives free sequencing for diverse applications. The company's goal is to make high-quality sequencing accessible and affordable to accelerate advancements in biotechnology.

San Diego, CaliforniaHeadquarters

2017Year Founded

$659.5MTotal Funding

SERIES_DCompany Stage

Biotechnology, HealthcareIndustries

201-500Employees

Benefits

100% company-paid medical, dental, & vision coverage

Flexible spending & health savings accounts

Premier mental health care

401(k) with immediately vested 4% company match

Company-paid Life and AD&D insurance

Stock option grants

Flexible time off

10 paid annual holidays

8-weeks paid parental leave

Risks

Increased competition from companies like Illumina may impact market share.

Rapid technological advancements require continuous innovation, straining resources.

High cost of AVITI24 may limit adoption among smaller research institutions.

Differentiation

Element Biosciences offers the AVITI System, a low-cost, high-quality sequencing platform.

The company's proprietary technology improves signal-to-noise ratio, enhancing sequencing data quality.

Strategic partnerships with firms like QIAGEN provide comprehensive NGS workflows for clients.

Upsides

AVITI24 platform integrates sequencing and multiomic analysis, revolutionizing cancer research.

Record growth in AVITI System installations indicates strong market demand and acceptance.

Recent executive appointments highlight commitment to leveraging AI for product optimization.

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