Sr. Scientist - Content Development at Alamar Biosciences

Fremont, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Life Sciences, DiagnosticsIndustries

Requirements

Ph.D. in Biochemistry, Molecular Biology, or a related discipline, with a minimum of 5 years of industrial experience
Hands-on experience in developing and optimizing immunoassays, ideally on high-sensitivity platforms (e.g., Simoa, MSD, or Luminex)
Strong expertise in assay prototyping, development, and control system design
Familiarity with regulatory expectations and best practices for assay development, including verification and validation workflows
Experience in multiplex assay development and troubleshooting is highly desirable
Proficiency in data management systems and tools is highly beneficial
Excellent organizational, documentation, and communication skills, with the ability to clearly convey complex scientific concepts to multidisciplinary teams
Proactive, adaptable, and self-motivated, with a strong “can-do” attitude and the ability to lead complex projects to completion

Responsibilities

Design, execute, and troubleshoot NULISA experiments for various biomarkers across diverse biological matrices (e.g., plasma, CSF, serum), ensuring high-quality, reproducible data
Develop and optimize assay parameters to meet performance requirements, including sensitivity, specificity, dynamic range, precision, and robustness
Evaluate and integrate novel technologies, reagents, and workflow improvements to enhance assay performance and scalability for both singleplex and multiplex formats
Perform rigorous data analysis using appropriate bioanalytical and statistical tools to determine key assay performance characteristics (e.g., LoD, LLoQ, precision, linearity, specificity, stability)
Work cross-functionally with internal teams and external partners to ensure the timely and accurate execution of project deliverables
Act as a subject matter expert (SME) within the technical core team, supporting risk assessments, design reviews, and root cause investigations related to assay development challenges
Provide technical mentorship and hands-on training to junior scientists and cross-functional stakeholders, fostering a collaborative and knowledge-sharing culture
Author, maintain, and review assay development documentation, including technical reports, SOPs, and work instructions, ensuring traceability and compliance with industry standards

Skills

NULISA

assay design

assay optimization

biomarker detection

proteomics

multiplex assays

data analysis

statistical tools

bioanalytical tools

plasma

CSF

serum

LoD

LLoQ

troubleshooting

Alamar Biosciences

Develops technology for protein detection and measurement

About Alamar Biosciences

Alamar Biosciences focuses on the study of proteins, known as proteomics, to enhance disease detection and treatment. The company has created NULISA™, a technology that can detect and measure proteins in the human body with high sensitivity and a wide range. This allows researchers and clinicians to profile clinically relevant protein biomarkers, which are essential for developing new diagnostic tests and treatments for various diseases. Alamar's ARGO™ system complements NULISA™ by providing a fully automated, high-throughput platform for precision proteomics. Unlike competitors, Alamar's technology simplifies the process, reducing the need for extensive technical expertise, making it more accessible to clients. The goal of Alamar Biosciences is to improve our understanding of proteins in health and disease, ultimately leading to better early detection and treatment options.

Hayward, CaliforniaHeadquarters

2018Year Founded

$225.7MTotal Funding

GRANTCompany Stage

Biotechnology, HealthcareIndustries

51-200Employees

Benefits

401(k) Company Match

401(k) Retirement Plan

Performance Bonus

Company Equity

Risks

Increased competition from Olink and SomaLogic may impact Alamar's market share.

Scaling production in Europe and APAC could strain resources and affect quality.

Regulatory hurdles in new regions may delay product launches and affect revenue.

Differentiation

Alamar's NULISA™ technology offers unprecedented sensitivity in protein detection.

The ARGO™ system automates high-throughput proteomics, reducing the need for technical expertise.

Alamar's focus on early disease detection sets it apart in the biotechnology field.

Upsides

ISO 13485:2016 certification boosts Alamar's credibility in the medical device industry.

European expansion with Milan headquarters enhances market reach and client service.

$10M investment accelerates Alzheimer's diagnostics development, strengthening Alamar's market position.

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