Spring 2026 Co-op: Lung Biology at Prime Medicine

Cambridge, Massachusetts, United States

Prime Medicine Logo
Not SpecifiedCompensation
InternshipExperience Level
InternshipJob Type
UnknownVisa
BiotechnologyIndustries

Requirements

  • Bachelors/Masters candidate in Biology-related major
  • Direct experience performing routine wet lab procedures and experiments
  • Hands on experience with sterile techniques and culturing of mammalian cell culture including primary cells
  • Experience with tissue sample preparation and immunostaining assays (flow cytometry, FACS, ICC/IHC) is a plus
  • Local to Boston/Cambridge area
  • Preferred Qualifications
  • Flow cytometry/FACS experience, including sample preparation and data analysis
  • In vitro molecular assays such as PCR/RT-qPCR
  • Gene editing technologies and viral and/or non-viral delivery

Responsibilities

  • Keen interest in learning and performing the downstream analysis of in vivo studies, including tissue sample preparation, in vitro assays (PCR and Next-gen sequencing) and data analysis
  • Set up air–liquid cultures of human bronchial epithelial cells and maintain them throughout the experimental period
  • Plan and execute in vitro assays to evaluate gene editing activity in relevant primary cell models
  • Follow protocols, standard operating procedures, execute assigned tasks and maintain ELN. Share responsibility in lab reagent inventory and maintaining equipment
  • Work and collaborate cross-functionally with colleagues. Collect, analyze and present data in team meetings

Skills

flow cytometry
tissue processing
air-liquid interface cultures
ALI cultures
cell culture
in vitro studies
in vivo studies
preclinical studies

Prime Medicine

Gene editing technology for genetic diseases

About Prime Medicine

Prime Medicine focuses on gene editing, specifically using a technology called Prime Editing to make precise changes to DNA. This technology can identify and fix faulty DNA segments, which helps restore normal genetic function. The company aims to cure, halt, or prevent genetic diseases, providing long-term benefits to patients. Prime Medicine targets individuals with genetic disorders, a significant market globally. Unlike many competitors, it emphasizes collaboration with research institutions and pharmaceutical companies to advance its technology and bring it to market through licensing agreements and partnerships. The leadership team has extensive experience in developing innovative medicines, and the company is committed to enhancing its technological capabilities.

Cambridge, MassachusettsHeadquarters
2019Year Founded
$306.4MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
201-500Employees

Benefits

Flexible Work Hours

Risks

Intellectual property disputes may lead to costly legal battles and delays.
The competitive landscape in gene editing is intensifying, challenging Prime Medicine's market position.
Reliance on partnerships exposes Prime Medicine to risks if collaborations don't meet expectations.

Differentiation

Prime Editing offers precise DNA modifications without double-stranded breaks, unlike CRISPR.
Prime Medicine's technology can correct faulty DNA segments, restoring normal genetic function.
The company collaborates with top-tier partners like Bristol Myers Squibb for strategic growth.

Upsides

Prime Medicine secured $244.6M to advance its genetic therapies and pipeline.
The partnership with Bristol Myers Squibb includes potential milestone payments over $3.5 billion.
Growing interest in gene editing for rare diseases boosts investment and collaboration opportunities.

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