Senior Scientist, High Throughput Biology (Contract) at Abata Therapeutics

South San Francisco, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Drug DiscoveryIndustries

Requirements

Ph.D. in Genetics, Molecular Biology, Cell Biology, Biochemistry, Functional Genomics, or related field, with 1-3 years of postdoctoral or industry experience
Proficiency with molecular biology techniques, complex library construction, flow cytometry, and cell line engineering
Experience with high throughput antibody display technologies, including yeast, phage, or mammalian display (plus)
Strong analytical skills and the ability to troubleshoot complex experimental issues independently
Strong data analysis capabilities, including proficiency with visualization and statistical software (e.g., GraphPad Prism, R, Python)
Excellent written and verbal communication skills; ability to present scientific findings clearly and concisely to diverse audiences
Enthusiastic team player who can work effectively across interdisciplinary teams
Strong technical expertise & laboratory skills
Excellent written and oral communication skills
Ability to work productively in a collaborative cross-functional team environment
Keeps current with the field of expertise, including literature and technology development

Responsibilities

Design, implement, and scale high-throughput functional screening strategies for binder discovery and lead characterization in mammalian systems
Evaluate and pilot emerging technologies and experimental workflows
Develop and optimize automated workflows, ensuring data quality, reproducibility, and process efficiency
Partner with drug discovery, computational biology, and AI-based protein design teams to analyze, interpret, and share insights from screening data
Independently manage multiple projects, ensuring timely delivery of high-quality data and adherence to team goals
Maintain accurate records of experiments, protocols, and findings, and contribute to internal and external scientific presentations

Skills

high-throughput screening

functional genomics

mammalian systems

automated workflows

data analysis

computational biology

protein design

AI models

Abata Therapeutics

Develops therapies for autoimmune diseases

About Abata Therapeutics

Abata Therapeutics develops therapies for autoimmune diseases, focusing on type 1 diabetes. Their main product, ABA 201, is a Treg cell therapy aimed at patients with some remaining beta cell function. This therapy works by utilizing regulatory T cells to improve patient outcomes. Unlike many competitors, Abata targets a specific niche within the autoimmune disease market and collaborates with partners like ElevateBio for process development and manufacturing. The company's goal is to transform treatment options for autoimmune diseases through advanced research and development.

Cambridge, MassachusettsHeadquarters

2021Year Founded

$184.8MTotal Funding

EARLY_VCCompany Stage

BiotechnologyIndustries

11-50Employees

Risks

Intensifying competition from companies like Sangamo Therapeutics may impact Abata's market share.

Stringent FDA scrutiny on manufacturing could delay Abata's clinical trials.

Rising clinical trial costs pose financial risks to Abata's pipeline progression.

Differentiation

Abata focuses on Treg cell therapies for autoimmune diseases like MS and diabetes.

Their lead product, ABA 201, targets type 1 diabetes with remaining beta cell function.

Abata's strategic partnership with ElevateBio enhances their manufacturing capabilities.

Upsides

Recent investment from Bristol Myers Squibb boosts Abata's Treg therapy pipeline development.

FDA's accelerated approval pathways may expedite Abata's clinical trials.

Growing autoimmune disease prevalence increases demand for Abata's innovative treatments.

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