Senior Scientist at Lyell Immunopharma

Washington, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

PhD in cell biology, immunology or related field with at least six years’ relevant industry experience, or MS with at least 11 years of relevant industry experience
A minimum of 10 years of extensive experience in developing flow-based assays
Expertise in flow cytometry-based assay development
Experience with analytical testing methodologies
Understanding of technological requirements for testing and characterization in a cellular therapy company

Responsibilities

Design, develop, execute, and document flow cytometry analytical methods for release testing and to study processes for production of T cell therapies
Critically analyze, interpret complex data, and draw appropriate conclusions
Support product characterization activities, including comparability assessments in support of product life cycle management
Act as a subject matter expert in providing analytical and data interpretation both internally and externally
Partner in the transfer of qualified assays to QC, and support assay validation and investigations
Responsible for completion of assignments that have an impact on functional goals
Develop and deliver scientific presentations, prepare clear and concise technical reports, participate in project teams, and contribute to regulatory filings, as needed
Participate in the evaluation of new analytical technologies and their implementation
Revise, review, and author assay standard operating procedures
Contribute to building a culture that encourages continuous learning, improvement, and innovation, and encourages team members to expand their technical skill base
Lead a group within Analytical Development and mentor scientists
Hands-on assay development and driving projects in close collaboration across TechOps and research
Work closely with other members of the analytical development team to develop strategy, conduct experiments, develop test methods, and assist in the tech transfer of analytical methodologies into a GMP manufacturing and QC testing facility

Skills

Flow Cytometry

Assay Development

T-cell Characterization

Analytical Development

CAR T-cell Therapies

Cell Therapy

Process Analytics

T-cell Biology

Lyell Immunopharma

Develops advanced cell therapies for cancer

About Lyell Immunopharma

Lyell Immunopharma develops advanced cell therapies aimed at treating solid tumors, which are cancerous tissue masses. The company focuses on enhancing T cells, a type of immune cell, to effectively target and eliminate cancer cells. Their approach includes genetic and epigenetic reprogramming of T cells to address challenges like T cell exhaustion and to ensure T cells can persist in the body. Unlike many competitors, Lyell is dedicated to creating curative treatments specifically for solid tumors, utilizing a diverse product pipeline that explores various treatment methods. The goal is to push the limits of current cancer therapies and provide effective solutions where traditional treatments have not succeeded.

San Francisco, CaliforniaHeadquarters

2018Year Founded

$479.6MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

201-500Employees