Senior Scientist at Lyell Immunopharma

Washington, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

PhD in cell biology, immunology or related field with at least six years’ relevant industry experience, or MS with at least 11 years of relevant industry experience
A minimum of 10 years of extensive experience in developing flow-based assays
Expertise in flow cytometry-based assay development
Experience with analytical testing methodologies
Understanding of technological requirements for testing and characterization in a cellular therapy company

Responsibilities

Design, develop, execute, and document flow cytometry analytical methods for release testing and to study processes for production of T cell therapies
Critically analyze, interpret complex data, and draw appropriate conclusions
Support product characterization activities, including comparability assessments in support of product life cycle management
Act as a subject matter expert in providing analytical and data interpretation both internally and externally
Partner in the transfer of qualified assays to QC, and support assay validation and investigations
Responsible for completion of assignments that have an impact on functional goals
Develop and deliver scientific presentations, prepare clear and concise technical reports, participate in project teams, and contribute to regulatory filings, as needed
Participate in the evaluation of new analytical technologies and their implementation
Revise, review, and author assay standard operating procedures
Contribute to building a culture that encourages continuous learning, improvement, and innovation, and encourages team members to expand their technical skill base
Lead a group within Analytical Development and mentor scientists
Hands-on assay development and driving projects in close collaboration across TechOps and research
Work closely with other members of the analytical development team to develop strategy, conduct experiments, develop test methods, and assist in the tech transfer of analytical methodologies into a GMP manufacturing and QC testing facility

Skills

Key technologies and capabilities for this role

Flow CytometryAssay DevelopmentT-cell CharacterizationAnalytical DevelopmentCAR T-cell TherapiesCell TherapyProcess AnalyticsT-cell Biology

Questions & Answers

Common questions about this position

What is the salary range for the Senior Scientist position?

This information is not specified in the job description.

Is this Senior Scientist role remote or onsite?

This information is not specified in the job description.

What key skills are required for the Senior Scientist, Analytical Development role?

Expertise in flow cytometry-based assay development, experience with analytical testing methodologies, and understanding of testing and characterization needs for cellular therapy are required. The role also involves leading a group, mentoring scientists, and hands-on assay development.

What is the company culture like at Lyell Immunopharma?

The culture is based on Science, Respect, Collaboration, and Courage, reflecting the team, environment, and the urgency of their mission.

What makes a candidate stand out for this Senior Scientist position?

Candidates with expertise in flow cytometry assay development for T-cell therapies, leadership experience in mentoring scientists, and the ability to collaborate across teams in analytical development will stand out.

Lyell Immunopharma

Develops advanced cell therapies for cancer

About Lyell Immunopharma

Lyell Immunopharma develops advanced cell therapies aimed at treating solid tumors, which are cancerous tissue masses. The company focuses on enhancing T cells, a type of immune cell, to effectively target and eliminate cancer cells. Their approach includes genetic and epigenetic reprogramming of T cells to address challenges like T cell exhaustion and to ensure T cells can persist in the body. Unlike many competitors, Lyell is dedicated to creating curative treatments specifically for solid tumors, utilizing a diverse product pipeline that explores various treatment methods. The goal is to push the limits of current cancer therapies and provide effective solutions where traditional treatments have not succeeded.

San Francisco, CaliforniaHeadquarters

2018Year Founded

$479.6MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

201-500Employees