Senior Associate Scientist, Pharmacology at Bristol-Myers Squibb

San Diego, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Pharmaceuticals, OncologyIndustries

Requirements

B.Sc. with 4–5+ years of experience
Experience designing and executing in vivo studies using CDX, PDX, and syngeneic mouse models
Proficiency in essential in vivo procedures: cell culture, tumor cell and PDX fragment implantation, sampling, dosing (IV, SC, IP, PO), tumor and body weight monitoring, and necropsy
Ability to analyze and interpret experimental data independently
Experience conducting in vitro experiments (e.g., cell viability, cytotoxicity, proliferation, apoptosis, DNA damage response, pathway interrogation) using molecular biology techniques
Ability to work with radioactive materials in strict compliance with institutional and federal radiation safety protocols
Knowledge of laboratory operations, inventory management, equipment maintenance, and compliance with company policies, GLP, IACUC, and animal welfare guidelines
Strong documentation skills in laboratory notebooks and electronic records
Effective collaboration skills within teams and cross-functionally
Initiative and technical expertise in troubleshooting experimental issues and ensuring accurate data analysis
Willingness to work outside standard business hours, including weekends, holidays, and early mornings

Responsibilities

Design and execute in vivo studies using CDX, PDX, and syngeneic mouse models to evaluate tumor growth kinetics, biodistribution, therapeutic efficacy, and durability of response across various treatment modalities, including radiopharmaceutical agents
Perform essential in vivo procedures: cell culture, tumor cell and PDX fragment implantation, sampling, dosing (IV, SC, IP, PO), tumor and body weight monitoring, and necropsy
Analyze and interpret experimental data independently; present findings at project team meetings, departmental reviews, and company-wide forums
Conduct in vitro experiments (e.g., cell viability, cytotoxicity, proliferation, apoptosis, DNA damage response, pathway interrogation) using molecular biology techniques
Work with radioactive materials in strict compliance with institutional and federal radiation safety protocols
Support laboratory operations, including inventory management, equipment maintenance, and ensure strict compliance with company policies, GLP, IACUC, and animal welfare guidelines, including accurate documentation in laboratory notebooks and electronic records
Collaborate effectively within the immediate team and cross-functionally to advance program objectives
Demonstrate initiative and technical expertise in troubleshooting experimental issues and ensuring accurate data analysis
Participate in discovery and translational research by conducting in vivo experiments and managing vivarium duties, including experiment design, execution, tissue collection, and data analysis
Engage in cross-functional collaboration with teams in translational research, medicinal chemistry, and other scientific disciplines

Skills

in vivo experiments

pharmacology

translational research

radiopharmaceuticals

biotechnology

oncology

laboratory techniques

drug discovery

Bristol-Myers Squibb

Develops and delivers biopharmaceutical medicines

About Bristol-Myers Squibb

Bristol Myers Squibb (BMS) develops and delivers medicines aimed at treating serious diseases, focusing on areas like cancer, autoimmune diseases, and heart conditions. The company conducts extensive research and development to create new drugs, which are sold after receiving regulatory approval. BMS also produces generic drugs, offering affordable alternatives that meet the same quality standards as their branded counterparts. What sets BMS apart from competitors is its dual focus on both innovative and generic medicines, enhancing access to healthcare. The company's goal is to improve patient outcomes while maintaining a commitment to sustainability and corporate responsibility.

New York City, New YorkHeadquarters

1887Year Founded

$33,706.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Flexible Work Hours

Hybrid Work Options

Professional Development Budget

Risks

Increased competition in oncology from emerging biotech firms like ArsenalBio.

BMS's lawsuit over the 340B Drug Pricing Program may lead to regulatory challenges.

Rapid AI and digital tech evolution may pose integration challenges for BMS.

Differentiation

BMS focuses on innovative cancer treatments through collaborations like ArsenalBio for T cell therapies.

The company emphasizes digital health technologies, enhancing clinical trial management and patient engagement.

BMS offers both innovative and generic medicines, increasing affordable healthcare solutions.

Upsides

BMS's partnership with Medidata enhances clinical research processes and patient outcomes.

The collaboration with AI Proteins advances novel miniprotein-based therapeutics, expanding therapeutic modalities.

BMS's global license agreement with BioArctic expands its portfolio in neurodegenerative diseases.

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