Scientist, NGS & Cell Engineering (BHN - Chicago) at Chan Zuckerberg Biohub

Chicago, Illinois, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, GenomicsIndustries

Requirements

PhD (or MS + 6-8 years of research experience) in Molecular Biology, Biotechnology, Genomics, or a related field
Extensive experience (5+ years) with NGS technologies, including short- and long-read sequencing
Expertise in molecular and cell biology techniques, including cloning, CRISPR-based genome editing, lentiviral transduction, and synthetic biology
Strong troubleshooting skills in developing and optimizing complex sequencing assays
Ability to communicate effectively across interdisciplinary teams, including biologists, data scientists, and engineers
Proficiency in data analysis and workflow scripting tools using Python (preferred) or R. (Nice to have)
Experience expressing and characterizing T Cell Receptors via in vitro assays (co-culture, tetramer staining, etc). (Nice to have)
Experience with multi-omics approaches, including single-cell and spatial transcriptomics. (Nice to have)
Background in high throughput screening, molecular assay development, or immunology. (Nice to have)

Responsibilities

Develop and troubleshoot novel NGS-based assays and improve existing workflows to maximize data quality and reproducibility
Design and execute cell engineering experiments, including cloning, lentiviral transduction, CRISPR modification, and other synthetic biology techniques
Collaborate with computational scientists and AI researchers to generate, analyze, and interpret sequencing data that will drive innovative model training
Standardize and document protocols, ensuring reproducibility and scalability across projects
Perform and interpret data analysis, presenting findings in lab meetings, internal seminars, and external conferences

Skills

Key technologies and capabilities for this role

NGSmolecular biologycell engineeringlentiviral transductionCRISPRcloning

Questions & Answers

Common questions about this position

What qualifications are required for the Scientist position?

A PhD (or MS + 6-8 years of research experience) in Molecular Biology, Biotechnology, Genomics, or a related field is required, along with 5+ years of experience with NGS technologies and expertise in molecular and cell biology techniques like cloning, CRISPR, and lentiviral transduction.

Is this role remote or based in a specific location?

This role is based out of the Chicago location.

What is the salary or compensation for this position?

This information is not specified in the job description.

What is the team and culture like at CZ Biohub Network?

The team brings together scientists, engineers, and physicians to pursue grand scientific challenges, emphasizing diversity of thought, ideas, and perspectives for disruptive innovation, in a dynamic and interdisciplinary environment.

What makes a strong candidate for this Scientist role?

Strong candidates will have strong troubleshooting skills in developing and optimizing complex sequencing assays, plus the ability to communicate effectively across interdisciplinary teams including biologists, data scientists, and engineers.

Chan Zuckerberg Biohub

Nonprofit research center for disease understanding

About Chan Zuckerberg Biohub

The Chan Zuckerberg Biohub focuses on biomedical research and technology development. It collaborates with top universities to study the basic mechanisms of diseases and create new diagnostic tools and therapies. The Biohub combines the expertise of engineers, data scientists, and researchers to tackle complex health challenges. Unlike many research institutions, it emphasizes a collaborative approach, pooling resources and knowledge from multiple prestigious universities. The goal of the Chan Zuckerberg Biohub is to advance scientific understanding and improve health outcomes through innovative research.

San Francisco, CaliforniaHeadquarters

2016Year Founded

VENTURE_UNKNOWNCompany Stage

Data & Analytics, BiotechnologyIndustries

51-200Employees

Benefits

Health Insurance

Life Insurance

Disability Insurance

401(k) Company Match

Family Planning Benefits

Fertility Treatment Support

Childcare Support

Unlimited Paid Time Off

Paid Vacation

Risks

Expansion may strain resources and management capabilities.

Potential ethical concerns with AI model reliance.

Collaboration with multiple universities could lead to intellectual property disputes.

Differentiation

CZ Biohub unites top universities for collaborative biomedical research.

Focus on AI-driven models for disease detection and treatment.

Pioneering cellular endoscopes for early disease monitoring and intervention.

Upsides

Expansion into New York enhances collaboration with leading institutions.

AI initiatives align with growing trends in drug discovery and precision medicine.

Genomic training initiatives support underrepresented medical students.

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