Scientist III (Oligonucleotides - Pharma) at Thermo Fisher Scientific

Athlone, County Westmeath, Ireland

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Not SpecifiedCompensation

Mid-level (3 to 4 years), Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceutical, Biotechnology, Life SciencesIndustries

Requirements

Educated to a bachelor's degree level in a relevant area (e.g., chemistry, biochemistry)
5+ years’ relevant industry experience within a GMP laboratory
5+ years’ analytical experience with oligonucleotide molecules (ASO and siRNA) for both Drug Product and Drug Substance
Proficient in Waters and Agilent HPLC and UPLC models and various detectors (UV, DAD/PDA, ELSD)
Experience with HPLC: Purity and impurity analysis of Denaturing and Non-denaturing HPLC Ion chromatography methods
Experience with Agilent and Waters HPLC and UPLC models and various detectors (UV, DAD/PDA, ELSD)
Integration of oligonucleotide chromatographic profiles
Empower apex track and traditional integration algorithm experience

Responsibilities

Perform a variety of complex sample preparations
Perform analysis procedures to quantitatively measure pharmaceutical compounds in a variety of formations for stability testing and other studies for analytical testing support
Review and compilation of results
Perform work assignments accurately, timely and in a safe manner
Train on routine operation, maintenance and theory of analytical instrumentation, SOPs, and regulatory procedures and guidelines
Work with multiple functional groups to meet business needs
Set up and maintain analytical instrumentation
Ensure QA findings are addressed appropriately
Communicate project status to project leader
Review, interpret, and analyze data for technical, quality and compliance to protocols, methods, SOPs, client criteria and Good Manufacturing Practices (GMP) or Good Laboratory Practices (GLP)
Interpret analytical data in regard to acceptability and consistency

Skills

Oligonucleotides

GMP

Sample Preparation

Analytical Instrumentation

Small Molecule Analysis

Quantitative Analysis

Data Interpretation

Thermo Fisher Scientific

Provides life sciences products and services

About Thermo Fisher Scientific

Thermo Fisher Scientific offers a variety of products and services that support scientific research and healthcare, including laboratory equipment, reagents, and software solutions. Their products are used in applications like protein biology, real-time PCR, and sequencing, serving clients such as academic institutions and pharmaceutical companies. Unlike competitors, Thermo Fisher emphasizes customer support and education, helping clients optimize their experiments. The company's goal is to be a leading provider of life sciences solutions that contribute to a healthier and safer world.

Waltham, MassachusettsHeadquarters

1956Year Founded

$17MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Increased competition in single-use bioprocessing may impact market share.

Sale of anatomical pathology business could create a temporary product gap.

Investment in miDiagnostics may face regulatory challenges affecting returns.

Differentiation

Thermo Fisher offers a comprehensive range of life sciences products and services.

Their well-known brands include Thermo Scientific, Applied Biosystems, and Invitrogen.

They provide strong customer support and educational resources to optimize client workflows.

Upsides

Expansion of biologics production facility enhances capacity for precision biologics monitoring.

Investment in miDiagnostics aligns with demand for rapid diagnostic solutions in BioPharma.

Collaboration with Mainz Biomed positions them in the growing cancer detection market.

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