Research Associate, In Vivo Pharmacology at Seismic

Cambridge, Massachusetts, United States

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Not SpecifiedCompensation

Junior (1 to 2 years), Mid-level (3 to 4 years)Experience Level

Full TimeJob Type

UnknownVisa

BiotechnologyIndustries

Requirements

BS/MS in Neuroscience, Physiology, Molecular/Cellular Biology, or a related Life Science discipline, with 0-2 years’ experience working in a life science research lab
Hands-on experience working with rodent animal models (mouse or rat) – including animal handling and husbandry
Candidates with experience in post-hoc procedures including tissue extraction, embedding and processing, immunohistochemistry (IHC), protein/nucleic acid extractions and/or PCR based methods (e.g., qPCR, ddpCR) will be preferred
Additional experience with one of the following methods will be a plus: in situ Hybridization (ISH), RNAscope, imaging/microscopy, image analysis as well protein detection/quantification methods such as Western Blot, ELISA, etc
Familiarity with various dosing routes in mice – including (but not limited to) Intracerebroventricular (ICV), intrathecal (IT), Intravenous (IV), Intra-muscular (IM), Intraparenchymal routes – is desirable
Experience with mouse/rat behavior assays (e.g. open field, rotarod) would be good to have but not required
Ability to work collaboratively with colleagues and effectively handle and prioritize multiple tasks in a fluid, fast-paced work environment
Ability to master new concepts quickly, highly organized, with excellent oral and written communication skills

Responsibilities

Establish and quantify readouts for in vivo efficacy, biodistribution, and other effects of dosed articles in animal models of rare genetic disorders
Maintain, genotype and characterize mutant mouse lines and their associated phenotypes, as well as assist with animal husbandry
Execute and/or troubleshoot diverse assays – physiological, behavioral, or tissue-based - perform relevant analysis, document all experimental details and results
Assist with experiments using cultured cells, virus vector production and/or titration and execute assays for DNA/RNA and/or protein quantification
Perform surgical procedures on animal models using multiple dosing routes
Work with team members to regularly update electronic lab notebook (ELN), prepare high quality reports and scientific presentations
Be up to date with relevant scientific literature and adapt to changes in priorities

Skills

Key technologies and capabilities for this role

In Vivo PharmacologyAnimal ModelsGenotypingMouse HusbandryBehavioral AssaysPhysiological AssaysTissue AnalysisCell CultureVirus Vector ProductionNeuroscienceGene Therapy

Questions & Answers

Common questions about this position

What qualifications and experience are required for the Research Associate position?

A BS/MS in Neuroscience, Physiology, Molecular/Cellular Biology, or a related Life Science discipline with 0-2 years’ experience in a life science research lab is required, along with hands-on experience working with rodent animal models including handling and husbandry.

What are the key responsibilities of the Research Associate role?

Key responsibilities include establishing and quantifying readouts for in vivo efficacy in animal models, maintaining and genotyping mutant mouse lines, executing diverse assays, assisting with cell and virus experiments, performing surgical procedures, and updating lab notebooks and presentations.

Is this position remote or on-site?

This information is not specified in the job description.

What is the salary or compensation for this role?

This information is not specified in the job description.

What preferred experiences will make my application stand out?

Experience in post-hoc procedures like tissue extraction, immunohistochemistry (IHC), protein/nucleic acid extractions, and PCR-based methods (e.g., qPCR, ddPCR) is preferred, and additional experience with certain methods is a plus.

Seismic

Sales enablement platform using AI technology

About Seismic

Seismic provides a platform designed to enhance the effectiveness of customer-facing teams, particularly in sales. The platform offers tools, content, and insights that help these teams improve customer experiences and drive business growth. It utilizes artificial intelligence to deliver insights that enable sales professionals to tailor their messages to meet customer needs at the right moment. This approach helps sales teams increase their productivity and engagement with customers. Seismic differentiates itself from competitors by focusing on AI-driven solutions and maintaining a strong commitment to research and development, ensuring they stay updated with the latest technological advancements. The company's goal is to empower businesses to optimize their sales processes and enhance customer interactions through a subscription-based model that provides ongoing access to their platform.

San Diego, CaliforniaHeadquarters

2010Year Founded

$434.3MTotal Funding

SERIES_GCompany Stage

Enterprise Software, AI & Machine LearningIndustries

1,001-5,000Employees

Benefits

Generous paid parental leave - Paid time off for moms and dads to spend time bonding with their new bundle of joy.

End-of-year paid recharge week - Our global offices shut down, allowing us all to unwind while we gear up for the new year ahead.

High performance bonus incentives - Employees are rewarded on a semi-annual basis for their awesome contributions to Seismic.

Global company meet-ups - An annual meet-up in sunny San Diego for a week of bonding, learning, and fun.

Risks

Emerging competition from Responsive's platform may challenge Seismic's market position.

Data privacy concerns may arise from Seismic's integration with Sales Copilot and People.ai.

AI regulations could impact Seismic's reliance on AI-driven features and innovations.

Differentiation

Seismic's AI-driven platform enhances sales productivity and customer engagement effectively.

The Seismic Enablement Cloud offers a unified platform for customer-facing teams globally.

Seismic's subscription model ensures a steady revenue stream for continuous platform improvement.

Upsides

Seismic's Winter 2024 release enhances personalization and sales efficiency with generative AI.

A $500M credit facility from PNC Bank supports Seismic's innovation and expansion plans.

Seismic's 'Market Leader' recognition boosts its market position and customer trust.

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