Research Associate, In Vivo Pharmacology at Seismic

Cambridge, Massachusetts, United States

Seismic Logo
Not SpecifiedCompensation
Junior (1 to 2 years), Mid-level (3 to 4 years)Experience Level
Full TimeJob Type
UnknownVisa
BiotechnologyIndustries

Requirements

  • BS/MS in Neuroscience, Physiology, Molecular/Cellular Biology, or a related Life Science discipline, with 0-2 years’ experience working in a life science research lab
  • Hands-on experience working with rodent animal models (mouse or rat) – including animal handling and husbandry
  • Candidates with experience in post-hoc procedures including tissue extraction, embedding and processing, immunohistochemistry (IHC), protein/nucleic acid extractions and/or PCR based methods (e.g., qPCR, ddpCR) will be preferred
  • Additional experience with one of the following methods will be a plus: in situ Hybridization (ISH), RNAscope, imaging/microscopy, image analysis as well protein detection/quantification methods such as Western Blot, ELISA, etc
  • Familiarity with various dosing routes in mice – including (but not limited to) Intracerebroventricular (ICV), intrathecal (IT), Intravenous (IV), Intra-muscular (IM), Intraparenchymal routes – is desirable
  • Experience with mouse/rat behavior assays (e.g. open field, rotarod) would be good to have but not required
  • Ability to work collaboratively with colleagues and effectively handle and prioritize multiple tasks in a fluid, fast-paced work environment
  • Ability to master new concepts quickly, highly organized, with excellent oral and written communication skills

Responsibilities

  • Establish and quantify readouts for in vivo efficacy, biodistribution, and other effects of dosed articles in animal models of rare genetic disorders
  • Maintain, genotype and characterize mutant mouse lines and their associated phenotypes, as well as assist with animal husbandry
  • Execute and/or troubleshoot diverse assays – physiological, behavioral, or tissue-based - perform relevant analysis, document all experimental details and results
  • Assist with experiments using cultured cells, virus vector production and/or titration and execute assays for DNA/RNA and/or protein quantification
  • Perform surgical procedures on animal models using multiple dosing routes
  • Work with team members to regularly update electronic lab notebook (ELN), prepare high quality reports and scientific presentations
  • Be up to date with relevant scientific literature and adapt to changes in priorities

Skills

In Vivo Pharmacology
Animal Models
Genotyping
Mouse Husbandry
Behavioral Assays
Physiological Assays
Tissue Analysis
Cell Culture
Virus Vector Production
Neuroscience
Gene Therapy

Seismic

Sales enablement platform using AI technology

About Seismic

Seismic provides a platform designed to enhance the effectiveness of customer-facing teams, particularly in sales. The platform offers tools, content, and insights that help these teams improve customer experiences and drive business growth. It utilizes artificial intelligence to deliver insights that enable sales professionals to tailor their messages to meet customer needs at the right moment. This approach helps sales teams increase their productivity and engagement with customers. Seismic differentiates itself from competitors by focusing on AI-driven solutions and maintaining a strong commitment to research and development, ensuring they stay updated with the latest technological advancements. The company's goal is to empower businesses to optimize their sales processes and enhance customer interactions through a subscription-based model that provides ongoing access to their platform.

San Diego, CaliforniaHeadquarters
2010Year Founded
$434.3MTotal Funding
SERIES_GCompany Stage
Enterprise Software, AI & Machine LearningIndustries
1,001-5,000Employees

Benefits

Generous paid parental leave - Paid time off for moms and dads to spend time bonding with their new bundle of joy.
End-of-year paid recharge week - Our global offices shut down, allowing us all to unwind while we gear up for the new year ahead.
High performance bonus incentives - Employees are rewarded on a semi-annual basis for their awesome contributions to Seismic.
Global company meet-ups - An annual meet-up in sunny San Diego for a week of bonding, learning, and fun.

Risks

Emerging competition from Responsive's platform may challenge Seismic's market position.
Data privacy concerns may arise from Seismic's integration with Sales Copilot and People.ai.
AI regulations could impact Seismic's reliance on AI-driven features and innovations.

Differentiation

Seismic's AI-driven platform enhances sales productivity and customer engagement effectively.
The Seismic Enablement Cloud offers a unified platform for customer-facing teams globally.
Seismic's subscription model ensures a steady revenue stream for continuous platform improvement.

Upsides

Seismic's Winter 2024 release enhances personalization and sales efficiency with generative AI.
A $500M credit facility from PNC Bank supports Seismic's innovation and expansion plans.
Seismic's 'Market Leader' recognition boosts its market position and customer trust.

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