Project Team Lead at Manifold Bio

Boston, Massachusetts, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

BiotechnologyIndustries

Requirements

A PhD degree in life sciences or a scientific discipline related to drug development; MD, PharmD or MS with strong scientific and drug development background also considered
At least 7 years of biotech/pharmaceutical industry experience in drug development, spanning from discovery through initiation of first-in-human clinical studies
Experience in discovery and development of biologic and/or oligonucleotide therapies, with a focus on neuroscience, motor, or cardiometabolic therapeutic areas preferred
Excellent knowledge of drug development processes and deliverables at each stage of the pipeline
Successful track record of leading projects/program teams in a cross-functional team environment from early discovery through IND-enabling activities and ideally through early clinical development
Experience successfully leading projects with participation by external collaborators
Experience in overs (incomplete in description)

Responsibilities

Provides strategic and scientific leadership for cross-functional project teams focused on the development of tissue-targeted therapeutic molecules as they transition from early discovery (lead identification) into early clinical development
Develops clear work plan that maps out timing and resourcing required to execute on critical path activities to progress novel lead tissue-targeted therapies from lead ID through early clinical testing, including candidate nomination, nonclinical PK and safety evaluation, CMC activities, regulatory submissions, and early clinical testing
Maintains team focus on efficient execution IND-enabling workplans. Works with project managers to track execution of critical path activities relative to target timelines and budget
Updates strategy based on emerging scientific data, changes in competitive landscape, and company strategic priorities; supports timely and clear project team decision-making that aligns with that strategy
Facilitates identification and resolution of issues/gaps; risks and risk-mitigation strategies. Prioritizes timely, resource-efficient solutions that are aligned with company priorities
Ensures cross-functional project team decisions are made in a timely manner and are aligned with company strategic priorities and latest scientific data
Advocates for the program with internal and external stakeholders; supports two-way communication between senior leadership and project team members. Ensures the opinions and perspectives of internal and external partners and stakeholders are heard and understood
Fosters a team culture of rigor, grit, accountability, and continuous improvement

Skills

Drug Discovery

Drug Development

Project Leadership

Cross-Functional Teams

Lead Identification

Candidate Nomination

Nonclinical PK

Safety Evaluation

CMC

Regulatory Submissions

Clinical Development

Tissue-Targeted Therapeutics

Manifold Bio

Designs precision biologics using in vivo methods

About Manifold Bio

Manifold Bio specializes in creating precision biologics for the pharmaceutical industry, focusing on drug design and development. Their main product is an in vivo drug design platform, which allows for testing drugs within living organisms rather than in laboratory settings. This platform utilizes mCodes™ technology, a unique protein barcoding system that enables the simultaneous study of multiple proteins in one experiment, making it particularly effective for complex biologics. Unlike other companies, Manifold Bio's approach to drug design is distinct because it integrates in vivo testing with advanced protein multiplexing capabilities. The company's goal is to expand their platform and collaborate with other pharmaceutical companies to develop new therapeutics.

Boston, MassachusettsHeadquarters

2020Year Founded

$58.8MTotal Funding

SERIES_ACompany Stage

Biotechnology, HealthcareIndustries

11-50Employees