Principal Site Reliability Engineer at Eli Lilly and Company

Hyderabad, Telangana, India

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Healthcare, Pharmaceuticals, TechnologyIndustries

Requirements

Demonstrate technical leadership and strategic thinking in SRE practices
Proactively identify and resolve reliability risks and bottlenecks
Foster strong cross-functional relationships with engineering, product, and operations teams
Lead by example in incident management, troubleshooting, and performance optimisation
Promote a culture of blamelessness (inferred from context)

Responsibilities

Lead the SRE team responsible for the reliability and performance of applications deployed on a cloud-native internal platform
Design, implement, and maintain automation frameworks, self-service tooling, and auto-healing systems to eliminate manual toil
Build and enhance end-to-end observability, monitoring, logging, and alerting systems for proactive issue detection and resolution
Ensure uptime: take ultimate ownership of production environment stability, lead end-to-end incident management from escalation to Root Cause Analysis (RCA), and manage patching, upgrades, and disaster recovery processes
Champion Infrastructure as Code (IaC) and CI/CD best practices for consistent, repeatable, and secure deployments
Collaborate with development and product teams to embed reliability and scalability into application design and architecture
Continuously evaluate and introduce emerging tools and technologies to keep the SRE stack modern and efficient
Mentor and guide SRE engineers, fostering a culture of ownership, innovation, and continuous improvement
Implement AIOps frameworks to improve operational tasks and enhance system self-healing capabilities
Participate in and optimise the on-call rotation, striving to minimise human intervention through automation
Drive capacity planning, disaster recovery, and business continuity initiatives
Support onboarding, documentation, and knowledge sharing for platform services and operational best practices

Skills

Key technologies and capabilities for this role

Site Reliability EngineeringSREScalabilityOperational ExcellenceAutomationSelf-Healing SystemsLeadershipMentoringPlatform EngineeringBest Practices

Questions & Answers

Common questions about this position

What is the employment type for this Principal Site Reliability Engineer role?

The position is full-time employment.

Is this Principal Site Reliability Engineer role remote or office-based?

This information is not specified in the job description.

What are the key responsibilities for the Principal Site Reliability Engineer?

You will lead the SRE team for reliability and performance of cloud-native applications, design automation frameworks and self-service tooling, build observability systems, ensure uptime through incident management and disaster recovery, champion IaC and CI/CD practices, and collaborate with development teams.

What is the company culture like at Eli Lilly for this role?

Eli Lilly unites caring with discovery to make life better, puts people first, hires diverse technology professionals, and focuses on creating medicines through pioneering technologies like data-driven drug discovery.

What makes a strong candidate for the Principal Site Reliability Engineer position?

Strong candidates will have leadership experience in SRE, expertise in cloud-native platforms, automation, observability, incident management, IaC, and CI/CD, plus the ability to mentor teams and collaborate across functions to drive reliability and scalability.

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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