Post Doc Scientist- Oncology at Gilead Sciences

Foster City, California, United States

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Not SpecifiedCompensation

InternshipExperience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

Ph.D. in Cancer Biology, Molecular Biology, Genetics, or a related field
Strong background in cancer pharmacology, drug resistance, and functional genomics
Hands-on experience with CRISPR/Cas9, lentiviral systems, and mouse xenograft models
Proficiency in next-generation sequencing data analysis and interpretation (preferred)
First authorship in publications in peer-reviewed journals or accepted in a peer-reviewed journal
Demonstrated ability to work independently and collaboratively in a multidisciplinary team
Excellent communication and scientific writing skills

Responsibilities

Develop and characterize in vitro and in vivo resistance models using cancer cell lines and mouse xenograft tumor models
Perform multi-omics profiling (WES, RNA-seq, methylation analysis and other) to identify molecular alterations associated with acquired and intrinsic resistance
Conduct functional validation of candidate resistance mechanisms using gene editing and gain-of-function systems
Think critically and creatively while applying strong organizational and planning skills
Actively participate in cross-functional group collaborations
Present at company internal meetings as well as at national or international scientific conferences

Skills

Key technologies and capabilities for this role

oncology researchresistance mechanismssmall molecule therapeuticsin vitro modelsin vivo modelscancer biologyscientific publications

Questions & Answers

Common questions about this position

What is the duration of this postdoctoral position?

The position is a 2-year term with an option to extend for an additional third year.

What qualifications are required for this Post Doc Scientist role?

Candidates need a Ph.D. in Cancer Biology, Molecular Biology, Genetics, or a related field, with a strong background in cancer pharmacology, drug resistance, and functional genomics.

What hands-on experience is needed for this position?

Hands-on experience with CRISPR/Cas9, lentiviral systems, and mouse xenograft models is required, along with proficiency in next-generation sequencing data analysis preferred.

What is the work environment like at Gilead for this role?

The role involves working in a highly collaborative environment with access to world-class research facilities and opportunities to leverage expertise across multiple functional areas.

What makes a strong candidate for this postdoctoral position?

A highly motivated and innovative candidate with a Ph.D., strong background in relevant fields, hands-on technical experience, and first authorship in peer-reviewed journals stands out.

Gilead Sciences

Develops and commercializes biopharmaceuticals

About Gilead Sciences

Gilead Sciences focuses on discovering, developing, and commercializing medicines for various medical conditions, including HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular issues. The company conducts extensive research and development to create new therapies, which are then marketed to healthcare providers, hospitals, and pharmacies after receiving regulatory approval. Gilead differentiates itself from competitors through its strong commitment to R&D and strategic partnerships, such as with SAP Ariba, to enhance its operations and product offerings. The company's goal is to improve health equity and access to care globally, working with communities to ensure that its medicines reach those in need.

Foster City, CaliforniaHeadquarters

1987Year Founded

$15,873.6MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Paid family time off and paid parental time off

Generous 401(k) contribution matching

Comprehensive medical plans that cover both physical and mental healthcare

Global Wellbeing Reimbursement

Time Off

Global Volunteer Day

Giving Together Program

Employee Support Programs

Flexible Work Options

Risks

Increased competition in HIV treatment from ViiV Healthcare's expanding drug portfolio.

Regulatory scrutiny over drug pricing could impact Gilead's U.S. market operations.

Patent expirations, like Truvada's, lead to increased generic competition and revenue loss.

Differentiation

Gilead's lenacapavir is recognized as the 2024 Breakthrough of the Year for HIV care.

Partnerships with LEO Pharma and Tubulis enhance Gilead's focus on inflammatory and cancer therapies.

Gilead's commitment to health equity initiatives like COMPASS and HepConnect sets it apart.

Upsides

Gilead's strategic partnerships expand its reach in inflammatory and oncology drug markets.

Investment in digital health technologies enhances Gilead's R&D and patient engagement.

Focus on sustainability improves Gilead's operational efficiency and corporate reputation.

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