CoOp, Computational Biology at Ginkgo Bioworks

Boston, Massachusetts, United States

Ginkgo Bioworks Logo
Not SpecifiedCompensation
InternshipExperience Level
InternshipJob Type
UnknownVisa
Biotechnology, Computational BiologyIndustries

Requirements

  • Eager to apply data science and computational biology to high-throughput datasets
  • Skilled in processing and analyzing transcriptomic datasets (e.g., Drug-seq)
  • Proficiency in rigorous QC, normalization, and differential expression analysis (DESeq2/edgeR)
  • Experience building reproducible pipelines (Snakemake/Nextflow) using R/Python
  • Ability to create clean analysis notebooks (R Markdown/Jupyter)
  • Knowledge of annotating results with pathways/ontologies (GSEA/fgsea, Enrichr) and public references
  • Capability to generate publication-quality visualizations
  • Comfortable collaborating with wet-lab scientists
  • Familiarity with contributing features/labels for AI/ML models (MoA/target inference, compound ranking)
  • Strong documentation and communication skills for sharing updates with stakeholders

Responsibilities

  • Process and analyze Drug-seq transcriptomic datasets from chemical libraries and CRISPR perturbation screens across multiple cell types
  • Perform rigorous QC, normalization, and differential expression (DESeq2/edgeR); aggregate and compare signatures across conditions
  • Build reproducible pipelines (Snakemake/Nextflow; R/Python) and clean analysis notebooks (R Markdown/Jupyter)
  • Annotate results with pathways/ontologies (GSEA/fgsea, Enrichr) and public references; generate publication-quality visualizations
  • Collaborate with wet-lab scientists to plan screens, define controls/replicates, and translate findings into actionable follow-ups
  • Contribute curated features/labels that help train and evaluate AI/ML models for MoA/target inference and compound ranking
  • Document methods and results; share concise updates with stakeholders

Skills

Key technologies and capabilities for this role

Drug-seqCRISPRDESeq2edgeRSnakemakeNextflowRPythonGSEAfgseaEnrichrR MarkdownJupyterdifferential expressionQCnormalization

Questions & Answers

Common questions about this position

What is the pay for this CoOp position?

The base salary is $25 hourly, with actual pay depending on skills, expertise, and experience. Additional compensation includes company stock awards.

What is the office attendance policy for this role?

Ginkgo has a return to office policy effective October 1, 2025, requiring in-office days on Tuesday, Wednesday, and Thursday for employees within 50 miles of offices in Boston, MA, Emeryville, CA, and West Sacramento, CA. Biosecurity positions are excluded from this policy.

What skills are required for this Computational Biology CoOp role?

Key skills include processing Drug-seq transcriptomic datasets, performing QC/normalization/differential expression with DESeq2/edgeR, building pipelines with Snakemake/Nextflow in R/Python, pathway annotation with GSEA/fgsea/Enrichr, and creating publication-quality visualizations.

What benefits does Ginkgo Bioworks offer for this role?

Benefits include a comprehensive package with medical, dental & vision coverage, health spending accounts, voluntary benefits, leave of absence policies, 401(k) with employer contribution, 8 paid holidays plus a full-week winter shutdown, and unlimited Paid Time Off.

What makes a strong candidate for this CoOp position?

A strong candidate is eager to apply data science and computational biology to high-throughput datasets, with skills in scalable analyses, reproducible pipelines, and collaboration with wet-lab scientists to deliver insights for AI models and hypotheses.

Ginkgo Bioworks

Programs cells to produce custom organisms

About Ginkgo Bioworks

Ginkgo Bioworks specializes in biotechnology by using advanced cell programming technology to create custom organisms that can produce various products, including food ingredients, fragrances, and therapeutics. Their platform allows them to design and grow these organisms, effectively turning cells into small factories that generate valuable compounds. Ginkgo collaborates with a wide range of clients, such as companies in the food and beverage sector, pharmaceuticals, agriculture, and biosecurity, to develop tailored biological solutions. This collaborative approach sets them apart from competitors, as they focus on partnerships to drive innovation and ensure a steady revenue stream through service fees, milestone payments, and royalties. The company's goal is to be a leader in the biotechnology field by providing custom solutions that meet the specific needs of their partners.

Boston, MassachusettsHeadquarters
2009Year Founded
$1,524.7MTotal Funding
IPOCompany Stage
Food & Agriculture, Biotechnology, HealthcareIndustries
1,001-5,000Employees

Benefits

Unlimited paid time off
Comprehensive health and parental leave benefits
Flexible work options
Commuter benefits
State-of-the-art labs, work spaces, and conference rooms
Competitive 401K contribution

Risks

Competition from Phytolon threatens Ginkgo's market share in food ingredients.
Lesaffre's acquisition of Altar may intensify competition in biotechnology.
Fluctuating fertilizer prices could impact Ginkgo's agricultural projects.

Differentiation

Ginkgo Bioworks leverages advanced cell programming to create custom organisms for diverse industries.
The company collaborates with industry leaders like Moderna and Cronos Group for innovative solutions.
Ginkgo's platform enables the design of organisms for food, pharmaceuticals, and biosecurity.

Upsides

Partnership with Carnegie Mellon boosts Ginkgo's presence in bioelectronic disease treatment.
Acquisition of StrideBio's assets expands Ginkgo's gene therapy capabilities.
Collaboration with NOVUS International enhances sustainable solutions in animal agriculture.

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