Staff Software Engineer - Instrument Software at Illumina

San Diego, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Genomics, BiotechnologyIndustries

Requirements

Strong proficiency in C# and .Net Core
Experience with Linux environments
Proven experience developing hardware abstraction layers and firmware/software integration
Deep understanding of service-oriented architecture, object-oriented analysis and design, event driven design, and other architectural patterns
Experience in REST API design
Multi-threading, synchronization, and concurrent programming
Bachelor's degree in Computer Science, Software Engineering, Electrical Engineering, or related field
8+ years of professional software development experience
Nice to Have: CI/CD pipeline design and implementation
Nice to Have: Static analysis tools and security scanning
Nice to Have: Performance profiling and optimization
Nice to Have: Proficiency with Atlassian tools like Jira and requirements management tools (like Jama)
Nice to Have: Basic proficiency in Typescript and Angular

Responsibilities

Own the architectural design and evolution of the HWI software subsystem, ensuring scalability, reliability, and maintainability
Drive subsystem-level architecture decisions and contribute to product-wide technical strategy
Define and enforce engineering standards, best practices, design patterns for hardware/software integration
Evaluate and introduce new technologies and tools to improve development efficiency
Design and develop critical HWI components using C#/.NET and Linux-based systems
Implement robust interfaces between Hardware Abstraction and Application Layers
Optimize system performance and resource utilization
Create comprehensive testing strategies including unit, automation, and hardware simulation
Independently investigate and resolve complex system-level issues
Proactively identify technical risks and develop mitigation strategies
Debug complex timing, concurrency, and hardware interaction issues
Perform root cause analysis and implement systemic improvements
Partner with hardware, firmware, and software teams to define interfaces and integration strategies
Mentor engineers in software design, debugging techniques, and best practices
Build strong relationships across product development functions to align technical solutions with business objectives
Communicate technical concepts effectively to both technical and non-technical stakeholders
Contribute to the long-term product roadmap and help define departmental technical goals

Skills

Key technologies and capabilities for this role

C#.NETLinuxSystem ArchitectureHardware IntegrationHardware AbstractionUnit TestingAutomation TestingHardware Simulation

Questions & Answers

Common questions about this position

What programming languages and technologies are required for this role?

The position requires strong proficiency in C# and .Net Core, experience with Linux environments, and proven experience developing hardware abstraction layers and firmware/software integration.

Is this a remote position or does it require working in an office?

This information is not specified in the job description.

What is the salary or compensation for this Staff Software Engineer role?

This information is not specified in the job description.

What does the company culture at Illumina feel like?

Illumina emphasizes working on impactful projects that transform human health, being surrounded by extraordinary people and inspiring leaders, with every role offering opportunities to make a difference.

What experience makes a candidate stand out for this position?

Candidates with strong proficiency in C#/.NET, Linux experience, hardware abstraction layer development, technical leadership in architecture, and mentorship skills will stand out.

Illumina

Supports genomics startups through funding and resources

About Illumina

Illumina focuses on fostering innovation in the genomics industry by supporting startups through its Illumina Accelerator program. This program helps entrepreneurs create, launch, and grow genomics-focused companies by providing funding and resources. The accelerator operates in two main locations: the San Francisco Bay Area and Cambridge, UK. Illumina Accelerator has successfully invested in 68 genomics startups, which have collectively raised over $1 billion in venture capital. What sets Illumina apart from its competitors is its strong partnership with leading venture capital investors and its dedicated focus on the genomics sector. The goal of Illumina is to build a thriving ecosystem for genomics innovation, enabling new companies to emerge and advance the field.

San Diego, CaliforniaHeadquarters

1998Year Founded

$27.2MTotal Funding

IPOCompany Stage

Venture Capital, BiotechnologyIndustries

5,001-10,000Employees

Risks

Over-reliance on NVIDIA's AI technology may limit flexibility in AI solution adoption.

Standardizing proteomics data across platforms could challenge Illumina's data reliability.

Single-flow-cell NovaSeq X System might cannibalize sales of higher-end models.

Differentiation

Illumina leads in genomic sequencing with advanced AI integration and multiomic data analysis.

The company offers innovative array-based solutions for DNA, RNA, and protein analysis.

Illumina's global expansion includes a new Global Capability Center in Bengaluru.

Upsides

Collaboration with NVIDIA enhances drug discovery and clinical development through AI integration.

Pilot proteomics program with UK Biobank aims to generate crucial reference datasets.

Single-cell sequencing kits make high-throughput sequencing accessible to smaller labs.

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