Senior Scientist, High-Content Imaging & Cell-Based Assay Development at Aegis Ventures

Berkeley, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

BiotechnologyIndustries

Requirements

Ph.D. in Cell Biology, Physiology, Pharmacology, Bioengineering, or related field with 5+ years industry experience in small-molecule drug discovery
Proven track record developing quantitative high-content imaging assays and phenotypic screens in mammalian systems
Hands-on expertise with 3D cultures and assay characterization for translational relevance
Experience with assay automation and miniaturization; strong understanding of plate-based statistics (Z’, %CV, S/B, controls)
Proficiency with imaging analysis platforms (e.g. ImageJ/Fiji, MetaXpress, Zen, CellProfiler); working ability in Python/R/SQL for image/feature analytics preferred
Demonstrated ability to lead projects and people in a fast-paced setting; excellent written and verbal communication skills
Passion for advancing therapies for kidney disease and solving complex biological problems with rigor and creativity

Responsibilities

Lead, mentor, and develop junior scientists; set goals, review data, and ensure on-time, high-quality execution
Design, optimize, and execute 2D and 3D cell-based imaging assays for phenotypic assay validation and MoA exploration
Establish rigorous QC metrics, TPP-aligned acceptance criteria, and SOPs enabling internal use and CRO tech transfer
Build high-content screening workflows for target validation
Implement pipelines for image processing, feature extraction, normalization, and data visualization/dashboards; drive data-driven decision-making
Integrate automated liquid handling and scheduling (e.g., Tecan) to boost throughput and reproducibility; monitor assay health over time
Collaborate with medicinal chemistry and translational teams to align assays to program strategy and timelines
Manage external collaborations/CROs and contribute to study design, tech transfer, and data reviews
Stay current on advances in kidney disease biology, 3D models, imaging, and screening technologies; propose platform innovations
Communicate results and recommendations to internal/external stakeholders with clarity and influence. Effectively document experimental analyses

Skills

High-Content Imaging

Cell-Based Assay Development

3D Cellular Systems

Phenotypic Assays

Image Processing

Feature Extraction

Data Normalization

Data Visualization

Automated Liquid Handling

Tecan

QC Metrics

SOP Development

CRO Tech Transfer

Aegis Ventures

Startup studio for launching transformative companies

About Aegis Ventures

Aegis Ventures partners with entrepreneurs and industry leaders to create and grow companies that aim to address significant societal challenges. The company operates as a startup studio, providing resources and support to help launch and scale new ventures. Aegis focuses on developing businesses primarily in the fields of artificial intelligence and health technologies. Their approach involves combining innovative ideas with long-term financial backing to ensure sustainable growth. Aegis Ventures distinguishes itself from competitors by emphasizing the creation of companies that not only aim for profitability but also strive to improve healthcare quality, accessibility, and affordability, ultimately enhancing patient care and clinical decision-making.

New York City, New YorkHeadquarters

2020Year Founded

$26.3MTotal Funding

VENTURE_UNKNOWNCompany Stage

AI & Machine Learning, HealthcareIndustries

11-50Employees

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Flexible Work Hours

Company Equity

Wellness Program

Mental Health Support

Risks

Increased competition in AI healthcare startups may dilute market share.

AI reliance poses ethical and regulatory challenges in healthcare.

Partnership with Northwell Holdings may face integration challenges.

Differentiation

Aegis Ventures partners with industry leaders to launch transformative companies.

Focus on AI and health technologies for impactful societal solutions.

Unique collaboration with Northwell Holdings to create innovative healthcare platforms.

Upsides

AI-driven personalized medicine aligns with Aegis Ventures' healthcare innovation focus.

AI in telehealth improves patient engagement, benefiting Aegis' virtual care initiatives.

AI-based diagnostic tools support Optain's market entry and growth.

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