Translational Medical Scientist
NateraSalary not specified
Full Time
Mid-level (3 to 4 years), Senior (5 to 8 years)
Senior Research Associate, Genomics Hub at Altos Labs
San Francisco, California, United States
Not SpecifiedCompensation
Senior (5 to 8 years)Experience Level
Full TimeJob Type
UnknownVisa
Biotechnology, GenomicsIndustries
Requirements
- Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Genetics, Biotechnology, or a related field
- Minimum 5+ years of professional laboratory experience, including direct experience with NGS workflows
- In-depth, hands-on experience with NGS library preparation and QC, and excellent understanding of the underlying biochemistry
- Strong hands-on experience with other standard Molecular Biology techniques (i.e. nucleic acid extraction and QC, PCR/qPCR, primer design, etc.)
- Experience with reagent validation, protocol optimization, and troubleshooting
- Knowledge and hands-on experience with operating and troubleshooting sequencing platforms including MiSeq, NextSeq, and Oxford Nanopore sequencers
- Hands-on experience with bulk, single-cell, and single-nuclei assays
- Excellent organizational skills, meticulous attention to detail, and record-keeping, particularly in electronic lab notebooks (ELNs)
- Excellent oral and written communication skills
- Ability to use technical skills and effective time management to perform work efficiently and meet project timelines
- Strong interpersonal skills with a demonstrated ability to work both independently and collaboratively in a fast-paced, multidisciplinary environment, with a commitment to transparency and teamwork
- Preferred Qualifications
- Experience and/or familiarity with the application of spatial genomics technologies
- Experience and/or familiarity with histology workflows
- Experience with automation platforms
Responsibilities
- Ownership of NGS project workflows from sample intake, RNA/DNA extraction and QC, NGS library preparation and QC, loading sequencing libraries onto Illumina/Nanopore sequencers, and assessing data quality after sequencing
- Provide daily operational support for genomics instrumentation and service pipelines
- Assist with planning future expansions with genomics workflow infrastructure, instrumentation and assay pipelines
- Develop, optimize, implement, and standardize state-of-the-art genomics pipelines
- Maintain accurate and detailed digital records including electronic lab notebook entries
- Broadly support the Genomics Hub operations, including reagent/consumable purchasing, management and maintenance of equipment and instruments
- Provide excellent communication of current workflows and hub capabilities
- Interface with genomics team members, BAI researchers, and Scientific Operations team members to identify areas of genomics support and meet project milestones
Skills
NGS
RNA extraction
DNA extraction
Library preparation
QC
Illumina
Nanopore
Sequencing
Genomics pipelines
Workflow optimization
Altos Labs
Biotechnology focused on cell rejuvenation research
About Altos Labs
Altos Labs specializes in biotechnology with a focus on cell rejuvenation, aiming to restore cell health and resilience to reverse diseases and injuries. Their approach involves cellular rejuvenation programming, which enhances cells' ability to resist stressors that can lead to illness. Unlike competitors, Altos Labs emphasizes research and collaboration with other institutions to develop effective treatments. The company's goal is to improve patients' quality of life through breakthrough therapies.
Los Altos, CaliforniaHeadquarters
2021Year Founded
$3,180.8MTotal Funding
EARLY_VCCompany Stage
Biotechnology, HealthcareIndustries
501-1,000Employees