Senior Research Associate, Enzyme Development at Ultima Genomics

San Diego, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Genomics, Life SciencesIndustries

Requirements

BS in biological sciences or related field
3-4 years’ experience working in biotech industry, academic research, or manufacturing environment
Hands-on experience in microbial fermentation, protein expression, and purification
Ability to work independently with flexibility to adjust work schedule as needed to maintain efficiency of cell culturing and protein handling, including occasional early morning/nights and weekends
Ability to perform physical tasks, such as moving easily in a lab environment, frequent pipetting, intermittent standing, bending, crouching, pushing/pulling, lifting/moving/carrying heavy objects (up to 50 lbs)

Responsibilities

Perform standard molecular biology techniques such as plasmid minipreps, transformations, agarose gel electrophoresis, SDS gel electrophoresis
Perform protein expression in bacterial host using shaker flask and fermentation equipment, as well as protein purification using affinity and ion exchange chromatography
Conduct assay of reagents for purity and quality
Assist in development and optimization of new laboratory protocols, and in troubleshooting experiments as needed
Maintain laboratory equipment and inventory
Other job duties as assigned

Skills

Key technologies and capabilities for this role

molecular biologyplasmid miniprepstransformationsagarose gel electrophoresisSDS-PAGEprotein expressionbacterial hostshaker flaskfermentationprotein purificationaffinity chromatographyion exchange chromatographyDNA amplificationenzyme development

Questions & Answers

Common questions about this position

Is this position remote or on-site?

This is a full-time, on-site position at the Carlsbad, CA office.

What are the required qualifications for this role?

A BS in biological sciences or related field and 3-4 years’ experience working in biotech industry, academic research, or manufacturing environment are required.

What hands-on skills are needed for enzyme development?

Hands-on experience in microbial fermentation, protein expression, and purification is required, along with performing standard molecular biology techniques like plasmid minipreps, transformations, agarose gel electrophoresis, and SDS gel electrophoresis.

What is the company culture like at Ultima Genomics?

The company fosters a collaborative environment with a diverse team of experts across disciplines including chemists, engineers, biologists, and more, offering opportunities to learn new skills and contribute to R&D innovations.

What makes a strong candidate for this Senior Research Associate role?

Strong candidates have the ability to work independently, flexibility to adjust schedules including occasional early mornings, nights, and weekends, and physical capability to perform lab tasks like frequent pipetting and lifting up to 50 lbs.

Ultima Genomics

High-throughput genomic sequencing services

About Ultima Genomics

Ultima Genomics focuses on improving human health through advanced genomic sequencing technologies. The company processes large amounts of genetic data to provide insights into human biology and diseases. Its clients include academic researchers, pharmaceutical companies, and healthcare providers who need accurate genomic data for their work. The key feature of Ultima Genomics is its sequencing architecture, which allows for extensive data collection from samples, detection of small genetic variations, and routine testing for early disease detection. This capability gives clients access to high-quality genomic information that is essential for research and clinical applications. Ultima Genomics stands out from competitors by excelling in breadth, depth, and frequency of data collection, enabling significant advancements in genomics. The company's goal is to continuously innovate and expand its services to help clients achieve breakthroughs in understanding and treating diseases.

Newark, New JerseyHeadquarters

2016Year Founded

$587.7MTotal Funding

LATE_VCCompany Stage

Biotechnology, HealthcareIndustries

201-500Employees

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

401(k) Retirement Plan

Paid Holidays

Paid Vacation

Employee Assistance Program

Risks

Competition from Illumina and BGI threatens Ultima's market share in low-cost sequencing.

Rapid technological advancements may render Ultima's current technologies obsolete.

Ethical and privacy concerns could lead to regulatory challenges for Ultima Genomics.

Differentiation

Ultima Genomics offers a revolutionary sequencing architecture with the UG 100 platform.

The UG 100 system enables cost-effective sequencing, targeting the $100 genome milestone.

Ultima's technology provides ultra-high accuracy for detecting single nucleotide variants.

Upsides

Ultima's UG 100 platform was selected for the UK's largest proteomics study.

Collaborations with Labcorp and Hartwig Medical enhance Ultima's clinical applications.

The UG 100 system's low cost and high accuracy drive adoption in precision oncology.

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