Principal Scientist, Medicinal Chemistry at Johnson & Johnson

San Diego, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, HealthcareIndustries

Requirements

Ph.D. in synthetic organic chemistry and optionally 1-2 years post-doctoral experience with 4+ years of medicinal chemistry experience, or equivalent
Experienced medicinal chemist with outstanding organic synthesis expertise
Extensive experience in design and execution of multi-step organic synthesis
Ability to develop and execute clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies
Ability to independently design and synthesize drug-like molecules utilizing medicinal chemistry knowledge, SAR analysis, structural modeling, molecular design tools with an understanding of pharmacokinetics, pharmacodynamics, and optimal physicochemical properties
Strong communication and interpersonal skills to effectively influence in a collaborative multidisciplinary environment
Ideally some leadership experience

Responsibilities

Develop and execute clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies
Maintain a high level of productivity in the laboratory setting
Independently design and synthesize drug-like molecules utilizing medicinal chemistry knowledge, SAR analysis, structural modeling, molecular design tools with an understanding of pharmacokinetics, pharmacodynamics, and optimal physicochemical properties
Collaboratively support the advancement of compounds through in vitro and in vivo studies to identify development candidates
Collaborate with structure-based design and in silico design groups to rationally design molecules
Generate novel, testable hypotheses to enable clear decision making
Manage external synthesis support efforts in collaboration with External Discovery Chemistry and Discovery Process Research colleagues
Contribute to defining scientific strategies and goals within a project team setting
Present data and reports on project status at individual, group, departmental and organizational meetings
Draft, execute and serve as lead author on research published in peer reviewed journals and present work at scientific conferences
Collaboratively engage with the external scientific community

Skills

Medicinal Chemistry

Organic Synthesis

Small Molecule Drug Discovery

Targeted Protein Degradation

Ubiquitin Ligase

Synthetic Chemistry

Drug Discovery

Johnson & Johnson

Healthcare products in pharmaceuticals and devices.

About Johnson & Johnson

Johnson & Johnson operates in the healthcare sector with three main areas: pharmaceuticals, medical devices, and consumer health products. In the pharmaceuticals segment, the company develops prescription drugs for various medical conditions such as cancer and infectious diseases. The medical devices segment provides products used in surgeries and other medical procedures, while the consumer health segment offers over-the-counter products, including baby care and personal health items. Johnson & Johnson generates revenue through direct sales and partnerships, and it invests significantly in research and development to create new products that meet the needs of consumers and healthcare providers. The company stands out from competitors by emphasizing diversity, equity, and inclusion in its workplace, fostering an environment where employees can share their perspectives. Its goal is to improve patient outcomes and enhance the overall health and well-being of individuals globally.

New Brunswick, New JerseyHeadquarters

1886Year Founded

IPOCompany Stage

HealthcareIndustries

10,001+Employees

Risks

J&J faces a class action lawsuit in Australia over ineffective cold and flu medications.

Former J&J executives joining other firms could lead to increased competition.

Ongoing legal battles, like the lawsuit against Cigna, pose financial liabilities for J&J.

Differentiation

J&J operates in three segments: pharmaceuticals, medical devices, and consumer health.

The company invests heavily in R&D for innovative medical solutions and products.

J&J is committed to diversity, equity, and inclusion in its workplace culture.

Upsides

J&J's collaboration with Helsinki University Hospital focuses on value-based healthcare models.

The rise of personalized medicine offers J&J opportunities in targeted therapies.

Increased focus on digital health solutions presents expansion opportunities for J&J.

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