Principal Scientist, In Vivo Pharmacology, Oncology Discovery Biology at Bristol-Myers Squibb

Winter Garden, Florida, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

Strong foundational knowledge of building PK, PD, BioD and efficacy relationships in vivo
Expertise in employing innovative approaches and novel technologies to advance research molecules towards development candidate selection and IND
Ability to identify and develop state-of-the-art in vivo models, experimental protocols, and relevant assays
Capability to design, independently execute, and deliver experiments with comprehensive high-quality data sets to drive decision making
Skill in interpreting results of complex experiments and contributing to complex team problem resolution and goals
Demonstrated critical thinking to address project challenges and independently drive programs forward with a solution-oriented mindset
Ability to proactively foster relationships across disciplines to facilitate decision making

Responsibilities

Function as Pharmacology lead and provide support for T cell engager drug discovery programs
Work closely with project teams and key stakeholders to lead the development of in vivo strategies from target concept to Proof of Concept in patients, applying scientific and technical skills to complex projects
Characterize drug candidates in vivo as part of the lead selection process
Work with cross-functional teams to participate in development and implementation of program strategy, including integrating in vivo pharmacology strategy with toxicology and translational strategies to support regulatory filings
Use relevant information, technology, and resources to contribute to team goals

Skills

Key technologies and capabilities for this role

In Vivo PharmacologyOncologyCancer BiologyImmuno-oncologyDrug DiscoveryIn Vitro ModelsIn Vivo ModelsEx Vivo ModelsTranslational MedicineBiomarkersPatient Enrichment

Questions & Answers

Common questions about this position

What are the main responsibilities of the Principal Scientist role?

The role involves functioning as Pharmacology lead and providing support for T cell engager drug discovery programs, leading the development of in vivo strategies from target concept to Proof of Concept in patients, and characterizing drugs while demonstrating critical thinking to drive programs forward.

Where are the research sites located for this position?

The Oncology Thematic Research Center is centered at state-of-the-art research sites in Cambridge and Seattle, with the Bristol Myers Squibb research site in Cambridge Crossing highlighted.

What is the company culture like at Bristol Myers Squibb?

The culture is challenging, meaningful, and life-changing, with uniquely interesting work, opportunities to grow and thrive alongside high-achieving teams, and a focus on balance and flexibility.

What benefits does Bristol Myers Squibb offer?

The company offers a wide variety of competitive benefits, services, and programs that provide employees with resources to pursue their goals both at work and in their personal lives.

What makes a strong candidate for this Principal Scientist position?

Ideal candidates should have scientific and technical skills to lead in vivo strategies for T cell engager programs, demonstrate critical thinking and a solution-oriented mindset, and be able to independently drive complex projects forward.

Bristol-Myers Squibb

Develops and delivers biopharmaceutical medicines

About Bristol-Myers Squibb

Bristol Myers Squibb (BMS) develops and delivers medicines aimed at treating serious diseases, focusing on areas like cancer, autoimmune diseases, and heart conditions. The company conducts extensive research and development to create new drugs, which are sold after receiving regulatory approval. BMS also produces generic drugs, offering affordable alternatives that meet the same quality standards as their branded counterparts. What sets BMS apart from competitors is its dual focus on both innovative and generic medicines, enhancing access to healthcare. The company's goal is to improve patient outcomes while maintaining a commitment to sustainability and corporate responsibility.

New York City, New YorkHeadquarters

1887Year Founded

$33,706.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Benefits

Flexible Work Hours

Hybrid Work Options

Professional Development Budget

Risks

Increased competition in oncology from emerging biotech firms like ArsenalBio.

BMS's lawsuit over the 340B Drug Pricing Program may lead to regulatory challenges.

Rapid AI and digital tech evolution may pose integration challenges for BMS.

Differentiation

BMS focuses on innovative cancer treatments through collaborations like ArsenalBio for T cell therapies.

The company emphasizes digital health technologies, enhancing clinical trial management and patient engagement.

BMS offers both innovative and generic medicines, increasing affordable healthcare solutions.

Upsides

BMS's partnership with Medidata enhances clinical research processes and patient outcomes.

The collaboration with AI Proteins advances novel miniprotein-based therapeutics, expanding therapeutic modalities.

BMS's global license agreement with BioArctic expands its portfolio in neurodegenerative diseases.

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