Chemist/Senior Chemist ADC Drug-Linker Synthetic Process Development at Eli Lilly and Company

Indianapolis, Indiana, United States

Apply Now

Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, BiotechnologyIndustries

Requirements

Bachelor’s and/or Master’s degree in Organic Chemistry, Chemistry, Biochemistry, or a related field
0–2 years of experience in synthetic organic chemistry laboratory environment

Responsibilities

Synthesize complex payloads and drug-linkers for preclinical tox studies and collaborate across internal Lilly networks to implement and deliver material and information via technical reports
Collaborate with members of the Lilly Discovery chemistry teams to understand and validate requirements for synthesis scale up
Work closely with early phase Discovery and Toxicology groups to support new and emerging assets in the portfolio via synthetic material supply
Independently problem-solve in the laboratory setting to overcome synthetic challenges and improve upon existing workflows
Maintain laboratory equipment and manage laboratory inventory/consumables
Serve as key point of contact for laboratory troubleshooting and develop chemistry solutions for process development problems in ‘real-time.’
Execute laboratory experiments to obtain data to support process development, process characterization, and range-finding experiments
Support generating data to be used in regulatory filings
Author technical reports and CMC related documents

Skills

synthetic chemistry

drug-linker synthesis

ADC process development

small-molecule chemistry

cytotoxic compounds

process transfer

bioconjugates

highly-potent compounds

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

Land your dream remote job 3x faster with AI

Try Jobo Free