Sr. Principle AI Software Engineer at Eli Lilly and Company

Indianapolis, Indiana, United States

Apply Now

Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceutical, Healthcare, Life SciencesIndustries

Requirements

Bachelor’s, Master’s, or PhD degree in Computer Science, Engineering, or related field
8+ years of software engineering experience
2+ years architecting and deploying production AI systems
Proven success delivering AI solutions in regulated or enterprise-wide environments
Demonstrated experience building production applications with AI-powered development tools

Responsibilities

Architect and ship scalable autonomous agent platforms, owning the full stack from LLM integration to production deployment
Leverage Lilly Cortex to architect sophisticated agentic systems using Model Context Protocol (MCP) for tool integration, Agent-to-Agent (A2A) communication for multi-agent coordination, and dynamic UI frameworks
Use AI development tools like GitHub Copilot and LLM-driven workflows to accelerate development and set standards for engineering teams
Define the technical vision and make architectural decisions for Studio as the company’s AI business platform, scaling from prototype to enterprise
Mentor engineers on modern AI/ML practices, prompt engineering, and agentic patterns; build a high-trust, high-velocity team culture
Establish engineering standards including CI/CD for AI systems, evaluation frameworks, observability for agent workflows, and compliance patterns for regulated environments
Partner with product, operations, and business teams to identify high-leverage AI opportunities and ship features that drive metrics
Stay at the forefront of AI by evaluating new models, testing emerging frameworks, and integrating latest research into production

Skills

AI System Design

LLM Integration

Autonomous Agents

Multi-Agent Orchestration

Agent Architectures

Production AI Systems

Scalable AI Platforms

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

Land your dream remote job 3x faster with AI

Try Jobo Free