Senior Scientist/Principal Scientist – Biologics Analytical Sciences at Zoetis

Kalamazoo, Michigan, United States

Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Animal Health, Biotechnology, PharmaceuticalsIndustries

PhD or BS/MS in chemistry, biochemistry, engineering, biology or other related discipline, at least 1-3 years (PhD) or 8+ years (MS or BS) experience preferably in the biopharmaceutical or vaccine industry
Motivated self-starter with excellent oral and written communication skills
Experience with HPLC, mass spectrometry, electrophoresis
Experience in developing and validating biopharmaceutical analytical methods
Prepare comprehensive analytical reports and presentations, conveying findings to both technical and non-technical stakeholders
Strong problem-solving skills and a proactive attitude toward process improvement
Desired Qualifications
Proficiency in data analytics tools such as JMP, Tableau, and Minitab, with the ability to manipulate, analyze, and visualize complex data sets
Individual contributor with experience in multiple analytical techniques (HPLC, mass spectrometry, immunoassays, CGE, cIEF) used to assess quality attributes of biopharmaceutical or vaccines products in development
Familiarity with peptide mapping by LC-MS/MS (UHPLC and nanoLC), intact mass analysis, MS/MS for protein and carbohydrate structural elucidation
Skills and experience in statistical analysis of assays, design of experiments (DOE), technical problem solving and continuous improvement
Experience with biopharmaceutical development and product licensure
Familiarity with biopharmaceutical manufacturing processes

Lead, design and conduct laboratory experiments including analytical method development, validation and transfer. Primary assays will be HPLC, mass spectrometry, electrophoresis, spectrophotometric, and microplate assays
Represent Analytical Sciences at project team meetings and provide analytical support for antigen or antibody characterization in support of process development and establishment of analytical methods for release testing
Perform analytical methods necessary for the characterization and release of active biological ingredients, vaccine and biopharmaceutical products
Design, set up, and conduct stability and other hypothesis driven studies
Trend and report method/critical reagent performance data
Develop and/or adopt new analytical technology, as appropriate, to advance programs with significant analytical and timeline challenges
Documentation, reporting, and communication of results in electronic laboratory notebooks, technical reports, PowerPoint presentations, and oral presentations
Interface with other scientists in a variety of technical disciplines including process development, formulation development, clinical operations, quality control, quality assurance, discovery, and manufacturing
Have a basic understanding of and utilize the statistical methods employed in process control and method development. Partner with Statistics group to design experiments and report data
Assist in the preparation and writing of regulatory filings