Senior Scientist, Preclinical at Eli Lilly and Company

Toronto, Ontario, Canada

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, BiotechnologyIndustries

Requirements

MSci degree in Molecular Biology or a related field with 3-4 years of experience (preferred) or BSci degree with 6+ years of experience
Strong background in molecular biology and pharmacology in an oncology setting
Experience in animal handling, tumor cell implantation for developing in-vivo tumor models, tumor measurements, compound formulation, intravenous injections, and necropsy
Ability to observe typical business hours (Monday through Friday), with some weekend, holiday, and occasional evening weekday work as required
(Preferred) Strong experience with mammalian tissue culture; experience with 3D organoid cultures is an asset
(Preferred) Experience in developing IHC protocols and familiarity with tools for IHC image analysis and quantification
(Preferred) Experience with radioactivity
(Preferred) Experience with live animal procedures under anesthesia (such as imaging)
Highly motivated and passionate about scientific research; detail-oriented with strong organizational skills; adaptable in a fast-paced environment; innovative thinker with proactive problem-solving; strong interpersonal skills for cross-functional teams

Responsibilities

Independently design, execute, and interpret in-vivo pharmacology studies to support radioligand therapy development
Identify clinically relevant models and pilot growth curves and efficacy studies
Collaborate with the pathology core to develop IHC protocols for FFPE sample staining
Perform flow cytometry to analyze cell populations
Conduct in-vivo mechanism of action (MOA) studies
Manage studies through external vendors

Skills

in-vivo pharmacology

radioligand therapy

IHC protocols

flow cytometry

FFPE staining

tissue microarray

efficacy studies

growth curves

MOA studies

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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