Senior Scientist – Bioprocess Development at Ecolab

King of Prussia, Pennsylvania, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biopharmaceutical, BiotechnologyIndustries

Requirements

M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8 years of relevant industry experience in downstream process development for biologics, or Ph.D. with 5 years of experience
Demonstrated expertise in preparative chromatography and antibody purification
Proven ability to lead small scientific teams and manage lab operations
Preferred Qualifications
Hands-on experience with AKTA systems, Unicorn software, and high-throughput screening platforms (e.g., Tecan Te-Chrom)
Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy
Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation
Experience in client-facing or CDMO environments
Strong communication, organizational, and problem-solving skills
Working knowledge of statistical tools (e.g., JMP) and data analysis software

Responsibilities

Design, execute, and analyze chromatography-based purification processes (Protein A, ion exchange, HIC, etc.) for mAbs
Develop scalable, robust purification processes tailored to client molecules and manufacturing goals
Lead technology transfer activities to external manufacturing sites
Author technical reports, protocols, and support regulatory documentation
Collaborate directly with major biopharma clients to align on study design, timelines, and deliverables
Deliver high-quality experimental results that support client development pipelines and regulatory submissions
Serve as a trusted scientific partner, helping clients overcome technical challenges and accelerate their path to market
Oversee day-to-day lab operations, including equipment maintenance, inventory, and safety compliance
Mentor and guide junior scientists and research associates
Foster a culture of scientific rigor, operational discipline, and continuous improvement

Skills

Key technologies and capabilities for this role

ChromatographyProtein AIon ExchangeHICMonoclonal AntibodiesDownstream Process DevelopmentBioprocess DevelopmentTechnology TransferRegulatory DocumentationBiologics Purification

Questions & Answers

Common questions about this position

What is the compensation for this Senior Scientist role?

This information is not specified in the job description.

Is this position remote or does it require on-site work?

This information is not specified in the job description.

What are the minimum qualifications for this role?

Candidates need an M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8 years of relevant industry experience, or a Ph.D. with 5 years of experience in downstream process development for biologics, plus demonstrated expertise in preparative chromatography and antibody purification, and proven ability to lead small scientific teams and manage lab operations.

What kind of team will I be leading in this role?

You will guide a small team of junior scientists and research associates, overseeing day-to-day lab operations, mentoring staff, and fostering a culture of scientific rigor, operational discipline, and continuous improvement.

What makes a strong candidate for this Senior Scientist position?

Strong candidates have hands-on experience with AKTA systems, Unicorn software, high-throughput screening platforms, proficiency in analytical techniques like HPLC and ELISA, familiarity with tech transfer and cGMP standards, and experience in client-facing environments, along with strong communication and problem-solving skills.