Senior Scientist, Bioinformatics at Thermo Fisher Scientific

Singapore

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Life SciencesIndustries

Requirements

PhD in Bioinformatics, Computational Biology, Computer Science, or a related field with 3+ years of relevant experience, or MS with 5+ years of relevant experience
Validated experience in bioinformatics pipeline development and workflow automation using Python and Linux environments
Experience developing or maintaining bioinformatics tools or algorithms that have been published or released as software products
Strong programming skills in C/C++ and scripting for algorithm optimization
Hands-on experience with relational databases (PostgreSQL, MySQL, or equivalent) including schema design, query optimization, and data integration
Proven understanding of genomics data analysis, including sequence alignment, indel calling, and variant annotation
Familiarity with biological databases (NCBI, COSMIC, UCSC Genome Browser, etc.)
Proficiency with statistical and data science libraries (NumPy, SciPy, Pandas, scikit-learn, etc.)
Excellent problem-solving and debugging skills with attention to scalability and reproducibility
Ability to collaborate optimally in a multi-disciplinary, distributed work environment
Background in assay development or computational biology applications
Preferred Qualifications
Confirmed expertise in Nextflow, Snakemake, WDL, or similar workflow management systems
Familiarity with containerization (Docker, Singularity) and CI/CD practices for pipeline deployment
Implement and handle cloud-based infrastructure (AWS preferred) to support scalable and reproducible computational workflows
Experience deploying and maintaining computational workflows on cloud infrastructure (AWS or similar)
Experience optimizing workflows for high-performance computing (HPC) or cloud-native architectures

Responsibilities

Develop, maintain, and optimize bioinformatics pipelines and workflow automation for large-scale assay development
Build and support Python-based tools, C/C++ algorithms, and SQL databases used in assay design and data analysis
Perform and optimize sequence data analysis workflows for variant detection, indel identification, and alignment using tools like ClustalW, BLAST, BWA, or comparable methods
Collaborate with internal teams to align pipeline outputs with laboratory processes and data systems
Maintain version-controlled repositories, documentation, and reproducibility across computational workflows
Participate in the publication or productization of developed algorithms, pipelines, or tools

Skills

Python

C/C++

SQL

PostgreSQL

MySQL

Linux

bioinformatics pipelines

workflow automation

BLAST

BWA

ClustalW

sequence alignment

variant detection

Thermo Fisher Scientific

Provides life sciences products and services

About Thermo Fisher Scientific

Thermo Fisher Scientific offers a variety of products and services that support scientific research and healthcare, including laboratory equipment, reagents, and software solutions. Their products are used in applications like protein biology, real-time PCR, and sequencing, serving clients such as academic institutions and pharmaceutical companies. Unlike competitors, Thermo Fisher emphasizes customer support and education, helping clients optimize their experiments. The company's goal is to be a leading provider of life sciences solutions that contribute to a healthier and safer world.

Waltham, MassachusettsHeadquarters

1956Year Founded

$17MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Increased competition in single-use bioprocessing may impact market share.

Sale of anatomical pathology business could create a temporary product gap.

Investment in miDiagnostics may face regulatory challenges affecting returns.

Differentiation

Thermo Fisher offers a comprehensive range of life sciences products and services.

Their well-known brands include Thermo Scientific, Applied Biosystems, and Invitrogen.

They provide strong customer support and educational resources to optimize client workflows.

Upsides

Expansion of biologics production facility enhances capacity for precision biologics monitoring.

Investment in miDiagnostics aligns with demand for rapid diagnostic solutions in BioPharma.

Collaboration with Mainz Biomed positions them in the growing cancer detection market.

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