Senior Manager, Clinical Scientist at Vor Bio

Boston, Massachusetts, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

Advanced degree (PhD, PharmD, MD, or equivalent) in life sciences, medicine, or a related field
Minimum of 6 years in clinical research, with demonstrated leadership in clinical science roles
Familiar with digital tools such as data analytics or agility to use them
Ability to synthesize the information, good presentation skills and effective communication skills (verbal and written)

Responsibilities

Contributes to preparation and/or review of any documents related to the studies and requiring a scientific background (abbreviated protocol/protocol/amended protocol, informed consent form, presentations/communication to internal or external partners, study plans including medical monitoring plan, safety management plan, risk mitigation plan and recruitment materials)
Assists in preparing medical answers to questions from Health Authorities, IRB/Ethics Committees, investigators, experts involved in the study/project
Contributes to the definition of the critical data/processes/predefined deviations list, risks and Quality tolerance limits identification and monitoring, to implement/develop related sections of the study risk management plan
Is involved in the update of study documents, ensures eCRFs are aligned with protocol updates, and contributes to optimizing and documenting data collection processes to enhance quality and reduce complexity
Supports Medical Monitors in subject-level data reviews, including eligibility assessments and ongoing data monitoring, ensuring timely data entry, consistency, and integrity
Supports data cleaning and query resolution throughout the study and participates in final review activities leading up to database lock to ensure data accuracy and integrity
Collaborates with Medical and Clinical Operations teams in developing study-specific training materials and provides scientific support during investigator and study team trainings
Contributes to definition of the centralized monitoring strategy in consistency with the planned statistical analysis and is involved in study data validation and review processes, support the director for the Clinical Case review (safety events reported to GPV or safety events of special interest), notably to anticipate and prevent last minute queries or backlog and smoothen the process

Skills

Clinical Trials

Protocol Development

Medical Monitoring

Safety Management

Risk Management

Study Design

Database Lock

Informed Consent

Phase 3 Studies

Autoimmune Diseases

Vor Bio

Develops targeted therapies for blood cancers

About Vor Bio

Vor Biopharma focuses on developing treatments for blood cancers, particularly Acute Myeloid Leukemia (AML). Their approach is designed to protect healthy cells while specifically targeting and eliminating cancerous cells. This method aims to improve the effectiveness of blood cancer treatments. Vor Biopharma serves patients with blood cancers, their caregivers, and medical professionals in hospitals and oncology centers. What sets Vor Biopharma apart from competitors is their strong emphasis on research and development, investing significantly in scientific research to create a proprietary platform and pipeline of therapies. They generate revenue through partnerships with other pharmaceutical companies and licensing agreements, with the goal of commercializing their therapies after obtaining regulatory approval. The company's mission is to transform the treatment landscape for blood cancers by providing innovative therapies that prioritize patient safety and efficacy.

Cambridge, MassachusettsHeadquarters

2015Year Founded

$147.9MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

51-200Employees

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Paid Vacation

Parental Leave

401(k) Retirement Plan

401(k) Company Match

Commuter Benefits

Risks

Significant YTD price decline of -62.76% may affect investor confidence.

Key clinical trial data updates are not expected until 2025, causing uncertainty.

Increased competition from companies like Editas Medicine poses potential conflicts.

Differentiation

Vor Bio focuses on protecting healthy cells while targeting cancerous ones.

The company specializes in innovative treatments for blood cancers like AML.

Vor Bio's approach aligns with the rise of personalized medicine.

Upsides

Recent $55.6M funding supports clinical trials and extends cash runway to 2025.

FDA's acceptance of gene therapies may ease approval for Vor Bio's treatments.

Advancements in CRISPR technology enhance precision of Vor Bio's gene editing.

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