Scientist/Senior Scientist, Preclinical Development and Translational Science at Abata Therapeutics

New York, New York, United States

Abata Therapeutics Logo
Not SpecifiedCompensation
Mid-level (3 to 4 years), Senior (5 to 8 years)Experience Level
Full TimeJob Type
UnknownVisa
Biotechnology, OncologyIndustries

Requirements

  • MS in related field, PhD a plus but not required
  • 2+ years of industry experience in preclinical development and clinical oncology biomarker
  • 5+ years of hands-on lab experience with a range of relevant research techniques including cell-based assays, molecular biology, and histology. In vivo mouse experience is preferred
  • Knowledge of antibody drug conjugates (ADC) biology and broad experience with in vitro and in vivo ADC testing
  • Experience in the development and validation of biomarker assays suitable for clinical samples
  • Track record of successfully managing external projects with CRO’s from scoping to final data delivery
  • Understanding of the drug development process from target identification to marketing authorization
  • Basic understanding of regulatory aspects of medical diagnostics
  • Excellent communication, organizational, and problem-solving skills

Responsibilities

  • In collaboration with other members of the Translational Science and the Discovery Science team, design and execute experimental plans to answer important translational questions to inform clinical development plans
  • Coordinate and oversee studies at contract research organizations
  • Execution and development of existing and/or new assays and assay strategies related to biomarker application and validation
  • Coordinate activities and timelines with Development teams to ensure seamless execution of biomarker capabilities to support clinical trials
  • Work closely with relevant team members to analyze, interpret and communicate translational results
  • Assist in preparation of relevant documents and reports including meeting presentations, biomarker reports, and regulatory submission documents

Skills

Key technologies and capabilities for this role

preclinical developmenttranslational sciencebiomarkerslaboratory skillsoncologyKIF18A inhibitors

Questions & Answers

Common questions about this position

Is this role remote or in-office?

The job is based in NYC and requires a minimum of 80% in office time.

What salary or compensation does this position offer?

This information is not specified in the job description.

What are the key requirements for this Scientist/Senior Scientist role?

Candidates need an MS in a related field, strong laboratory skills, preclinical biomarker experience, and must be detail-oriented and self-motivated with highly relevant experience.

What is the company culture like at Volastra Therapeutics?

Volastra is a fast-paced biotech company of passionate employees with ample opportunity for growth and development, including chances to work on projects outside direct scope.

What makes a strong candidate for this position?

A strong candidate has strong laboratory skills, preclinical biomarker experience, is detail-oriented and self-motivated, and brings highly relevant experience to support preclinical development and translational science.

Abata Therapeutics

Develops therapies for autoimmune diseases

About Abata Therapeutics

Abata Therapeutics develops therapies for autoimmune diseases, focusing on type 1 diabetes. Their main product, ABA 201, is a Treg cell therapy aimed at patients with some remaining beta cell function. This therapy works by utilizing regulatory T cells to improve patient outcomes. Unlike many competitors, Abata targets a specific niche within the autoimmune disease market and collaborates with partners like ElevateBio for process development and manufacturing. The company's goal is to transform treatment options for autoimmune diseases through advanced research and development.

Cambridge, MassachusettsHeadquarters
2021Year Founded
$184.8MTotal Funding
EARLY_VCCompany Stage
BiotechnologyIndustries
11-50Employees

Risks

Intensifying competition from companies like Sangamo Therapeutics may impact Abata's market share.
Stringent FDA scrutiny on manufacturing could delay Abata's clinical trials.
Rising clinical trial costs pose financial risks to Abata's pipeline progression.

Differentiation

Abata focuses on Treg cell therapies for autoimmune diseases like MS and diabetes.
Their lead product, ABA 201, targets type 1 diabetes with remaining beta cell function.
Abata's strategic partnership with ElevateBio enhances their manufacturing capabilities.

Upsides

Recent investment from Bristol Myers Squibb boosts Abata's Treg therapy pipeline development.
FDA's accelerated approval pathways may expedite Abata's clinical trials.
Growing autoimmune disease prevalence increases demand for Abata's innovative treatments.

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