Scientist, In Vitro Pharmacology at Altos Labs

San Francisco, California, United States

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Not SpecifiedCompensation

Mid-level (3 to 4 years), Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

PhD in Pharmacology, Biology, Biochemistry, or a related field and a minimum of 2 years of industry experience in a drug discovery and development setting
Strong demonstrated experience conceptualizing and performing cellular, biochemical, and complex in vitro models with a background in relevant laboratory techniques and methods
Ability to independently design experiments and generate robust, reproducible, and generalizable results
Proven track record of elucidating complex biological mechanisms
Record of high productivity and ability to complete work in a timely manner
Proficient in documenting experimental design, analysis and interpretation of data in an electronic lab notebook
Excellent communication and presentation skills
Preferred Qualifications
Experience working on cellular and complex in vitro models of diverse age-related conditions
Expertise in brightfield and confocal microscopy techniques and experience with high-content screening instruments and image analysis
Cell engineering for the development of cellular models and reporter assays
Experience designing, implementing, and validating automated workflows for complex assays, ensuring high reproducibility and robustness, including proficiency in laboratory automation platforms (e.g., liquid handlers) and expertise in writing scripts (e.g., Python, R) to automate data acquisition, processing, normalization, and visualization
Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics

Responsibilities

Design, optimize, execute, and troubleshoot a range of assays, including cellular, biochemical, and complex in vitro models, to advance the drug discovery pipeline
Validate drug targets and define mechanisms of action (MoA) through robust in vitro pharmacology strategies, and support a diverse portfolio of early exploratory and drug-discovery stage projects
Analyze, interpret, and present experimental data to drive project strategy and key decision-making
Contemporaneously document all experimental methods, raw data, and results in an electronic laboratory notebook, ensuring reproducibility and data integrity
Partner with Institute of Science (IOS) labs and internal cross-functional groups to discover and validate novel drug targets
Collaborate with Technical Operations (Process Development and Analytical Development) to optimize processes and assays, ensuring smooth alignment with downstream operations
Maintain up-to-date knowledge of relevant scientific and technological advancements

Skills

in vitro pharmacology

cell-based assays

biochemical assays

in vitro models

drug discovery

assay optimization

troubleshooting

data analysis

mechanism of action

target validation

electronic laboratory notebook

Altos Labs

Biotechnology focused on cell rejuvenation research

About Altos Labs

Altos Labs specializes in biotechnology with a focus on cell rejuvenation, aiming to restore cell health and resilience to reverse diseases and injuries. Their approach involves cellular rejuvenation programming, which enhances cells' ability to resist stressors that can lead to illness. Unlike competitors, Altos Labs emphasizes research and collaboration with other institutions to develop effective treatments. The company's goal is to improve patients' quality of life through breakthrough therapies.

Los Altos, CaliforniaHeadquarters

2021Year Founded

$3,180.8MTotal Funding

EARLY_VCCompany Stage

Biotechnology, HealthcareIndustries

501-1,000Employees

Risks

Ethical concerns about lifespan extension may lead to regulatory challenges.

Intensifying competition in the biotechnology sector could dilute market share.

High expectations from financial backers may pressure the company to deliver quickly.

Differentiation

Altos Labs focuses on cellular rejuvenation to reverse diseases and improve health.

The company integrates computational biology and CRISPR technology for innovative solutions.

Altos Labs collaborates with leading scientists, including Nobel laureate Jennifer Doudna.

Upsides

Significant funding of $270 million supports Altos Labs' research and development efforts.

The economic potential of increased life expectancy is recognized as a major opportunity.

Collaborations with tech industry veterans accelerate innovation and commercialization.

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