Scientist, Biologics at Johnson & Johnson

Spring House, Pennsylvania, United States

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Not SpecifiedCompensation

Mid-level (3 to 4 years), Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, BiotechnologyIndustries

Requirements

A minimum of a Bachelor’s degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is required. Master’s degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is preferred
A minimum of 5 years of relevant industry experience with a Bachelor’s degree or a minimum of 3 years of relevant industry experience with a Master’s degree is required
Solid understanding of protein science and biophysical principles is required
Hands-on experience characterizing therapeutic proteins and antibodies using a broad array of biophysical and stability techniques, including SEC, DSF, HIC, GXII, and/or DLS is required
Experience with high-throughput liquid handling systems is preferred
Experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required
Must have excellent verbal and written communication skills
Must have strong interpersonal skills
The ability to report data and present findings to management is required

Responsibilities

Design and execute experiments to assess high-concentration properties of lead molecules, including viscosity, concentratability, stability, aggregation, and self-association
Set up and manage stability studies; prepare samples for biophysical analysis
Conduct high-throughput biophysical measurements using techniques such as NanoDSF, GXII, Chromatography (Size Exclusion (SEC), Hydrophobic Interaction (HIC), CIC), Capillary Isoelectric Focusing (cIEF), Dynamic Light Scattering (DLS), Mass photometry
Execute methods of automation workflows: execute methods on Liquid Handlers for sample preparation (mixing, dilution, plate transfer, plate mapping)
Independently interpret and communicate experimental results to program teams and senior management
Innovate and implement new techniques to assess developability and biophysical characteristics of therapeutic candidates
Optimize biophysics characterization workflows to improve throughput and data quality
Serve as a Biophysics representative on multidisciplinary project teams, contributing scientific insights and strategic direction

Skills

biophysical analysis

NanoDSF

GXII

SEC

HIC

CIC

cIEF

DLS

Mass photometry

stability studies

viscosity measurement

aggregation analysis

protein characterization

high-throughput screening

biotherapeutics R&D

Johnson & Johnson

Healthcare products in pharmaceuticals and devices.

About Johnson & Johnson

Johnson & Johnson operates in the healthcare sector with three main areas: pharmaceuticals, medical devices, and consumer health products. In the pharmaceuticals segment, the company develops prescription drugs for various medical conditions such as cancer and infectious diseases. The medical devices segment provides products used in surgeries and other medical procedures, while the consumer health segment offers over-the-counter products, including baby care and personal health items. Johnson & Johnson generates revenue through direct sales and partnerships, and it invests significantly in research and development to create new products that meet the needs of consumers and healthcare providers. The company stands out from competitors by emphasizing diversity, equity, and inclusion in its workplace, fostering an environment where employees can share their perspectives. Its goal is to improve patient outcomes and enhance the overall health and well-being of individuals globally.

New Brunswick, New JerseyHeadquarters

1886Year Founded

IPOCompany Stage

HealthcareIndustries

10,001+Employees

Risks

J&J faces a class action lawsuit in Australia over ineffective cold and flu medications.

Former J&J executives joining other firms could lead to increased competition.

Ongoing legal battles, like the lawsuit against Cigna, pose financial liabilities for J&J.

Differentiation

J&J operates in three segments: pharmaceuticals, medical devices, and consumer health.

The company invests heavily in R&D for innovative medical solutions and products.

J&J is committed to diversity, equity, and inclusion in its workplace culture.

Upsides

J&J's collaboration with Helsinki University Hospital focuses on value-based healthcare models.

The rise of personalized medicine offers J&J opportunities in targeted therapies.

Increased focus on digital health solutions presents expansion opportunities for J&J.

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