Principal Scientist, Cheminformatics (Small Molecule & DEL Informatics) at Johnson & Johnson

Spring House, Pennsylvania, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, Biotechnology, HealthcareIndustries

Requirements

PhD in Cheminformatics, Chemical Engineering, Computational Chemistry, or a related field
Minimum of 3 years of industry experience with a proven track record of delivering end-to-end solutions from conceptualization to implementation
Deep expertise in cheminformatics software (e.g., KNIME, OpenEye) and programming languages (e.g., Python, R)
Expertise in structure-activity relationship (SAR) analysis
Experience working in cross-functional teams & translating ideas

Responsibilities

Lead the development and implementation of advanced cheminformatics tools for small molecule analysis and DEL informatics
Implement statistical approaches to improve selection of compounds for off-DNA synthesis and accelerate workups of DEL screens
Enhance our internal DEL ML virtual screening capabilities and apply to key projects
Collaborate with interdisciplinary teams to integrate cheminformatics solutions into drug discovery platforms
Design and optimize computational workflows and front-ends for the analysis and visualization of small molecule bioactivity and ADMET data
Manage and mentor contractors, ensuring robust project delivery and performance
Stay updated on industry trends and emerging technologies in cheminformatics and DEL to enhance project outcomes

Skills

Cheminformatics

Small Molecule Informatics

DEL Informatics

Data Science

Computational Chemistry

Machine Learning

RDKit

Pipeline Pilot

KNIME

Python

SQL

Johnson & Johnson

Healthcare products in pharmaceuticals and devices.

About Johnson & Johnson

Johnson & Johnson operates in the healthcare sector with three main areas: pharmaceuticals, medical devices, and consumer health products. In the pharmaceuticals segment, the company develops prescription drugs for various medical conditions such as cancer and infectious diseases. The medical devices segment provides products used in surgeries and other medical procedures, while the consumer health segment offers over-the-counter products, including baby care and personal health items. Johnson & Johnson generates revenue through direct sales and partnerships, and it invests significantly in research and development to create new products that meet the needs of consumers and healthcare providers. The company stands out from competitors by emphasizing diversity, equity, and inclusion in its workplace, fostering an environment where employees can share their perspectives. Its goal is to improve patient outcomes and enhance the overall health and well-being of individuals globally.

New Brunswick, New JerseyHeadquarters

1886Year Founded

IPOCompany Stage

HealthcareIndustries

10,001+Employees

Risks

J&J faces a class action lawsuit in Australia over ineffective cold and flu medications.

Former J&J executives joining other firms could lead to increased competition.

Ongoing legal battles, like the lawsuit against Cigna, pose financial liabilities for J&J.

Differentiation

J&J operates in three segments: pharmaceuticals, medical devices, and consumer health.

The company invests heavily in R&D for innovative medical solutions and products.

J&J is committed to diversity, equity, and inclusion in its workplace culture.

Upsides

J&J's collaboration with Helsinki University Hospital focuses on value-based healthcare models.

The rise of personalized medicine offers J&J opportunities in targeted therapies.

Increased focus on digital health solutions presents expansion opportunities for J&J.

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